Morphine alkaloids: History, biology, and synthesis.

Alkaloids Biology Codeine Morphine
Alkaloids Analgesia Codeine Medicinal derivatives Morphine Opioids Opium Total synthesis

Journal

The Alkaloids. Chemistry and biology
ISSN: 1099-4831
Titre abrégé: Alkaloids Chem Biol
Pays: United States
ID NLM: 9812842

Informations de publication

Date de publication:
2021
Historique:
entrez: 27 9 2021
pubmed: 28 9 2021
medline: 26 10 2021
Statut: ppublish

Résumé

This chapter provides a short overview of the history of morphine since it's isolation by Sertürner in 1805. The biosynthesis of the title alkaloid as well as all total and formal syntheses of morphine and codeine published after 1996 are discussed in detail. The last section of this chapter provides a detailed overview of medicinally relevant derivatives of the title alkaloid.

Identifiants

DOI: 10.1016/bs.alkal.2021.04.001 PMID: 34565506
pubmed: 34565506
pii: S1099-4831(21)00018-3
doi: 10.1016/bs.alkal.2021.04.001
pii:
doi:

Substances chimiques

Alkaloids 0
Morphine 76I7G6D29C
Codeine UX6OWY2V7J

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

145-342

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Christopher Wicks (C)

Department of Chemistry and Centre for Biotechnology, Brock University, St. Catharines, ON, Canada.

Tomas Hudlicky (T)

Department of Chemistry and Centre for Biotechnology, Brock University, St. Catharines, ON, Canada.

Uwe Rinner (U)

IMC Fachhochschule Krems/IMC University of Applied Sciences Krems, Krems, Austria. Electronic address: uwe.rinner@fh-krems.ac.at.

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Alcaloïdes › Morphine alkaloids: History, biology, and synthesis.
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Morphine alkaloids: History, biology, and synthesis.
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › Morphinanes › Dérivés de la morphine › Codéine › Morphine alkaloids: History, biology, and synthesis.
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › Morphinanes › Dérivés de la morphine › Morphine › Morphine alkaloids: History, biology, and synthesis.