Porin 1 Modulates Autophagy in Yeast.
autophagy
phosphatidylethanolamine
phosphatidylserine decarboxylase
voltage dependent anion channel (VDAC)
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
14 09 2021
14 09 2021
Historique:
received:
20
08
2021
revised:
07
09
2021
accepted:
09
09
2021
entrez:
28
9
2021
pubmed:
29
9
2021
medline:
16
11
2021
Statut:
epublish
Résumé
Autophagy is a cellular recycling program which efficiently reduces the cellular burden of ageing. Autophagy is characterised by nucleation of isolation membranes, which grow in size and further expand to form autophagosomes, engulfing cellular material to be degraded by fusion with lysosomes (vacuole in yeast). Autophagosomal membranes do not bud from a single cell organelle, but are generated de novo. Several lipid sources for autophagosomal membranes have been identified, but the whole process of their generation is complex and not entirely understood. In this study, we investigated how the mitochondrial outer membrane protein porin 1 (Por1), the yeast orthologue of mammalian voltage-dependent anion channel (VDAC), affects autophagy in yeast. We show that
Identifiants
pubmed: 34572064
pii: cells10092416
doi: 10.3390/cells10092416
pmc: PMC8464718
pii:
doi:
Substances chimiques
Mitochondrial Proteins
0
Phosphatidylethanolamines
0
Por1 protein, S cerevisiae
0
Porins
0
Saccharomyces cerevisiae Proteins
0
phosphatidylethanolamine
39382-08-6
Carboxy-Lyases
EC 4.1.1.-
Psd1 protein, S cerevisiae
EC 4.1.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministerium für Kultur und Wissenschaft des Landes Nordrhein-Westfalen
ID : 311-8.03.03.02-142461
Organisme : Austrian Science Fund
ID : J3742-B28
Références
Mol Biol Cell. 2010 Jul 1;21(13):2270-84
pubmed: 20444982
Science. 2010 Jan 22;327(5964):425-31
pubmed: 20093466
EMBO J. 2011 Oct 18;30(21):4356-70
pubmed: 22009199
Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Jan;1862(1):81-89
pubmed: 27542541
J Mass Spectrom. 2012 Jan;47(1):96-104
pubmed: 22282095
Methods Enzymol. 2008;451:43-56
pubmed: 19185712
EMBO J. 2017 Jul 14;36(14):2018-2033
pubmed: 28550152
J Cell Biol. 1999 Oct 18;147(2):435-46
pubmed: 10525546
Cell Mol Life Sci. 2020 Aug;77(16):3195-3213
pubmed: 31655859
Curr Biol. 2014 Mar 17;24(6):609-20
pubmed: 24613307
Nat Rev Mol Cell Biol. 2018 Sep;19(9):579-593
pubmed: 30006559
Science. 2012 Nov 9;338(6108):815-8
pubmed: 23042293
Appl Environ Microbiol. 2013 Oct;79(20):6459-71
pubmed: 23956390
Cell. 2010 May 14;141(4):656-67
pubmed: 20478256
Dev Cell. 2018 Jan 22;44(2):261-270.e6
pubmed: 29290583
J Bacteriol. 1986 Mar;165(3):901-10
pubmed: 3005242
Yeast. 2004 Aug;21(11):947-62
pubmed: 15334558
J Cell Biol. 2008 Aug 25;182(4):685-701
pubmed: 18725538
Anal Chem. 2017 Jul 5;89(13):7046-7052
pubmed: 28570056
Mol Cell Biol. 1997 Oct;17(10):5727-38
pubmed: 9315631
Anal Chem. 2017 Dec 5;89(23):12857-12865
pubmed: 29111682
Cell Rep. 2017 Jun 27;19(13):2836-2852
pubmed: 28658629
Nat Commun. 2019 Mar 8;10(1):1130
pubmed: 30850607
PLoS Genet. 2014 May 01;10(5):e1004347
pubmed: 24785424
Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3179-88
pubmed: 26056272
J Biol Chem. 2012 Oct 26;287(44):36744-55
pubmed: 22984266
J Biol Chem. 2018 Nov 9;293(45):17593-17605
pubmed: 30237174
Nat Cell Biol. 2010 Aug;12(8):747-57
pubmed: 20639872
J Biol Chem. 1957 May;226(1):497-509
pubmed: 13428781
EBioMedicine. 2018 Apr;30:261-272
pubmed: 29606629
Nat Rev Mol Cell Biol. 2009 Jul;10(7):458-67
pubmed: 19491929
Nat Methods. 2012 Jun 28;9(7):676-82
pubmed: 22743772
Biochim Biophys Acta. 2004 Nov 8;1686(1-2):161-8
pubmed: 15522832
J Cell Sci. 2019 Jan 2;132(1):
pubmed: 30510114
Eukaryot Cell. 2012 Dec;11(12):1568-72
pubmed: 23104570
J Biol Chem. 2019 Aug 9;294(32):12020-12039
pubmed: 31209110
Cell Res. 2014 Jan;24(1):24-41
pubmed: 24366339
Autophagy. 2016;12(1):1-222
pubmed: 26799652
EMBO J. 1987 Mar;6(3):723-8
pubmed: 2438132
Nucleic Acids Res. 2012 Jan;40(Database issue):D700-5
pubmed: 22110037
J Biol Chem. 2013 Apr 26;288(17):11920-9
pubmed: 23471966
Mol Biol Cell. 2010 Jul 1;21(13):2257-69
pubmed: 20444978
J Cell Biol. 2011 Oct 17;195(2):323-40
pubmed: 21987634
Autophagy. 2015 Nov 2;11(11):2114-2122
pubmed: 26649943
Mol Cell. 2019 Mar 7;73(5):1044-1055.e8
pubmed: 30738703
Dev Cell. 2018 Apr 9;45(1):114-131.e8
pubmed: 29634932
Mol Cell. 2019 Mar 7;73(5):1056-1065.e7
pubmed: 30738704
Cold Spring Harb Protoc. 2017 May 1;2017(5):
pubmed: 28461652
Methods Mol Biol. 2006;313:75-84
pubmed: 16118426
Methods Enzymol. 2002;350:87-96
pubmed: 12073338
J Biol Chem. 2007 Jun 8;282(23):16736-43
pubmed: 17428789
EMBO J. 2015 Apr 15;34(8):1025-41
pubmed: 25586377
J Membr Biol. 1998 Jan 15;161(2):173-81
pubmed: 9435273
Sci Rep. 2016 Jun 14;6:27710
pubmed: 27295977
Cell. 2020 Jan 9;180(1):135-149.e14
pubmed: 31883797
Methods Enzymol. 2008;451:33-42
pubmed: 19185711
PLoS One. 2012;7(1):e29851
pubmed: 22272252
Cell Metab. 2014 Mar 4;19(3):431-44
pubmed: 24606900
J Cell Biol. 2006 Dec 18;175(6):901-11
pubmed: 17178908
EMBO J. 1983;2(12):2161-8
pubmed: 6321150
Science. 2009 Jul 24;325(5939):477-81
pubmed: 19556461
EMBO J. 2011 Jun 1;30(11):2101-14
pubmed: 21468027
Cell Death Differ. 2015 Mar;22(3):499-508
pubmed: 25571976
Methods Enzymol. 2017;588:367-394
pubmed: 28237110
EMBO J. 2015 Aug 13;34(16):2117-31
pubmed: 26162625
J Cell Biol. 2012 May 28;197(5):659-75
pubmed: 22613832
Methods Mol Biol. 2017;1619:203-212
pubmed: 28674888
Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15370-5
pubmed: 18832158
Biochim Biophys Acta. 2016 Oct;1863(10):2498-502
pubmed: 26826035
Nat Commun. 2020 Aug 13;11(1):4056
pubmed: 32792483
Nat Rev Mol Cell Biol. 2020 Jan;21(1):7-24
pubmed: 31732717
J Cell Biol. 2015 May 25;209(4):539-48
pubmed: 25987606
Elife. 2016 Apr 20;5:
pubmed: 27097106
Science. 2004 Jun 11;304(5677):1644-7
pubmed: 15192221
Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14151-6
pubmed: 21825164
PLoS Biol. 2014 Oct 14;12(10):e1001969
pubmed: 25313861