Unveiling the Metabolic Effects of Glycomacropeptide.
GLP-1
amino acids
glycomacropeptide
intact protein
metabolism
phenylketonuria
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
08 Sep 2021
08 Sep 2021
Historique:
received:
26
07
2021
revised:
26
08
2021
accepted:
27
08
2021
entrez:
28
9
2021
pubmed:
29
9
2021
medline:
29
10
2021
Statut:
epublish
Résumé
For many years, the main nitrogen source for patients with phenylketonuria (PKU) was phenylalanine-free amino acid supplements. Recently, casein glycomacropeptide (GMP) supplements have been prescribed due to its functional and sensorial properties. Nevertheless, many doubts still persist about the metabolic effects of GMP compared to free amino acids (fAA) and intact proteins such as casein (CAS). We endeavour to compare, in rats, the metabolic effects of different nitrogen sources. Twenty-four male Wistar rats were fed equal energy density diets plus CAS (control,
Identifiants
pubmed: 34575895
pii: ijms22189731
doi: 10.3390/ijms22189731
pmc: PMC8470927
pii:
doi:
Substances chimiques
Biomarkers
0
Caseins
0
Peptide Fragments
0
caseinomacropeptide
0
Glucose
IY9XDZ35W2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Norte2020 and Fundação para a Ciência e a Tecnologia (FCT)
ID : NORTE-08-5369-FSE-000018 and [UID/BIM/04293/2013]
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