[Progress in application of Bletilla striata polysaccharide in novel drug delivery systems and biomaterials].

Bletilla striata polysaccharide adhesion drug delivery effect-enhancing and toxicity-reducing targeting unification of medicines and excipients wound dressing

Journal

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
ISSN: 1001-5302
Titre abrégé: Zhongguo Zhong Yao Za Zhi
Pays: China
ID NLM: 8913656

Informations de publication

Date de publication:
Sep 2021
Historique:
entrez: 28 9 2021
pubmed: 29 9 2021
medline: 30 9 2021
Statut: ppublish

Résumé

As the main active ingredient of the orchidaceous herb Bletilla striata, B. striata polysaccharide(BSP) has pharmacological activities such as promoting coagulation, anti-inflammation, anti-oxidation, promoting wound healing, anti-tumor, and immunomodulation, and is biodegradable and non-toxic. Additionally, it has the material properties of suspension thickening, film-forming adhesion, coating and solubilizing, targeting and slow releasing, effect-enhancing and toxicity-reducing, etc., playing the role of unification of medicines and excipients. Therefore, BSP has a wide application prospect in the fields of drug delivery system and trauma repair. This paper reviews the research progress of BSP application in new drug delivery systems and biomaterials based on the related li-terature in recent years, with the aim of providing reference for the further research and application of BSP.

Identifiants

pubmed: 34581074
doi: 10.19540/j.cnki.cjcmm.20210528.604
doi:

Substances chimiques

Biocompatible Materials 0
Polysaccharides 0

Types de publication

Journal Article Review

Langues

chi

Sous-ensembles de citation

IM

Pagination

4666-4673

Auteurs

Zi-Hao Ma (ZH)

School of Pharmacy, Southwest Minzu University Chengdu 610041, China.

Jie Ma (J)

School of Pharmacy, Southwest Minzu University Chengdu 610041, China.

Jin-Ying Lyu (JY)

School of Pharmacy, Southwest Minzu University Chengdu 610041, China.

Juan He (J)

School of Pharmacy, Southwest Minzu University Chengdu 610041, China.

Duo-Wu-Ni Jia (DW)

School of Pharmacy, Southwest Minzu University Chengdu 610041, China.

Xiao Yang (X)

School of Pharmacy, Southwest Minzu University Chengdu 610041, China.

Yan Qu (Y)

School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611137, China.

Rui Zeng (R)

School of Pharmacy, Southwest Minzu University Chengdu 610041, China Science and Technology Department, Southwest Minzu University Chengdu 610041, China.

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Classifications MeSH