Epidemiological and clinical characteristics of the COVID-19 epidemic and associated factors for mortality in Golestan province, Iran: a retrospective cohort study.
Adult
Age Factors
Aged
Aged, 80 and over
COVID-19
/ epidemiology
Comorbidity
Female
Hospital Mortality
Hospitalization
/ statistics & numerical data
Humans
Iran
/ epidemiology
Male
Middle Aged
Pandemics
Respiratory Distress Syndrome
/ complications
Retrospective Studies
Risk Factors
SARS-CoV-2
Sex Factors
Acute Respiratory Distress Syndrome
COVID-19
Death
Iran
Journal
Journal of preventive medicine and hygiene
ISSN: 2421-4248
Titre abrégé: J Prev Med Hyg
Pays: Italy
ID NLM: 9214440
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
09
12
2020
accepted:
09
03
2021
entrez:
4
10
2021
pubmed:
5
10
2021
medline:
26
10
2021
Statut:
epublish
Résumé
We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia and risk factors associated for mortality. In this study, we included inpatient with acute respiratory distress syndrome at Golestan Hospitals who had been discharged or had died in 2020. Epidemiological, and clinical data were extracted from electronic medical records and compared between recovered and died cases. We used multiple logistic regression methods to explore the risk factors associated with in-hospital death. Overall 2,835 acute respiratory distress syndrome patients were included in this study, and 874 (30.83%) were positive for 2019-nCoV. Five hundred and sixty-three patients (19.86%) died, 1,687 patients (59.51%) were recovered. Of the total deaths, only 288 (10.15%) were attributed to COVID-19. The most common symptoms at onset of illness were respiratory distress [1,795 (63.32%)], fever [1,601 (56.47%)], dry cough [1,595 (56.26%)], sore throat [445 (15.70%)], and myalgia [342 (12.06%)]. One thousand and twelve (35.7%) had 1 or more coexisting medical conditions. In multiple logistic regression analysis, risk factors associated with the death included older age [OR (Odds Ratio) = 1.03; 95% CI; 1.02-1.04], blood oxygen level (SPO The 2019-nCoV infection caused collections of severe respiratory illness and was associated to a high ratio of hospitalization in ICU and high mortality. Older age and comorbidities were associated with more risk of death among patients with 2019-nCoV.
Sections du résumé
BACKGROUND
BACKGROUND
We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia and risk factors associated for mortality.
METHODS
METHODS
In this study, we included inpatient with acute respiratory distress syndrome at Golestan Hospitals who had been discharged or had died in 2020. Epidemiological, and clinical data were extracted from electronic medical records and compared between recovered and died cases. We used multiple logistic regression methods to explore the risk factors associated with in-hospital death.
RESULTS
RESULTS
Overall 2,835 acute respiratory distress syndrome patients were included in this study, and 874 (30.83%) were positive for 2019-nCoV. Five hundred and sixty-three patients (19.86%) died, 1,687 patients (59.51%) were recovered. Of the total deaths, only 288 (10.15%) were attributed to COVID-19. The most common symptoms at onset of illness were respiratory distress [1,795 (63.32%)], fever [1,601 (56.47%)], dry cough [1,595 (56.26%)], sore throat [445 (15.70%)], and myalgia [342 (12.06%)]. One thousand and twelve (35.7%) had 1 or more coexisting medical conditions. In multiple logistic regression analysis, risk factors associated with the death included older age [OR (Odds Ratio) = 1.03; 95% CI; 1.02-1.04], blood oxygen level (SPO
CONCLUSIONS
CONCLUSIONS
The 2019-nCoV infection caused collections of severe respiratory illness and was associated to a high ratio of hospitalization in ICU and high mortality. Older age and comorbidities were associated with more risk of death among patients with 2019-nCoV.
Identifiants
pubmed: 34604569
doi: 10.15167/2421-4248/jpmh2021.62.2.1910
pmc: PMC8451345
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
E298-E304Informations de copyright
©2021 Pacini Editore SRL, Pisa, Italy.
Déclaration de conflit d'intérêts
Conflict of interest statement The authors declare no conflict of interest.
Références
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
Int J Health Policy Manag. 2014 Aug 13;3(3):123-8
pubmed: 25197676
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
PLoS Pathog. 2017 Nov 30;13(11):e1006698
pubmed: 29190287
Lancet Infect Dis. 2013 Sep;13(9):752-61
pubmed: 23891402
Int J Infect Dis. 2016 Aug;49:129-33
pubmed: 27352628
Iran J Public Health. 2020 Oct;49(Suppl 1):132-133
pubmed: 34268222
JAMA Intern Med. 2020 Jul 1;180(7):934-943
pubmed: 32167524
Lancet. 2020 Feb 15;395(10223):507-513
pubmed: 32007143
J Clin Virol. 2020 Jun;127:104378
pubmed: 32353762
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
N Engl J Med. 2003 May 15;348(20):1986-94
pubmed: 12682352
Arthritis Rheum. 2002 Jan;46(1):250-8
pubmed: 11817599
Respirology. 2018 Feb;23(2):130-137
pubmed: 29052924
Z Gesundh Wiss. 2020 Apr 30;:1-3
pubmed: 32355606
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Viruses. 2019 Jan 14;11(1):
pubmed: 30646565