Distinguishing Meningioma From Metastasis of Prostate Cancer on 68Ga-PSMA PET/CT.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
01 Nov 2021
01 Nov 2021
Historique:
entrez:
4
10
2021
pubmed:
5
10
2021
medline:
16
10
2021
Statut:
ppublish
Résumé
Meningiomas are typically benign and the most common primary brain tumors. They are usually diagnosed based on their characteristic appearance on both MRI and CT. Meningiomas can easily be misdiagnosed as metastasis of prostate cancer due to their high 68Ga-PSMA uptake on 68Ga-PSMA PET/CT. We present a case of a metastatic prostate adenocarcinoma with PSMA-avid lesion in the right frontal lobe on 68Ga-PSMA PET/CT. Later, MRI confirmed the brain lesion as meningioma.
Identifiants
pubmed: 34606488
doi: 10.1097/RLU.0000000000003629
pii: 00003072-202111000-00030
doi:
Substances chimiques
Gallium Isotopes
0
Gallium Radioisotopes
0
gallium 68 PSMA-11
0
Edetic Acid
9G34HU7RV0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e553-e555Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest and sources of funding: none declared.
Références
Afshar-Oromieh A, Malcher A, Eder M, et al. PET imaging with a [ 68 Ga] gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions. Eur J Nucl Med Mol Imaging . 2013;40:486–495.
Silver DA, Pellicer I, Fair WR, et al. Prostate-specific membrane antigen expression in normal and malignant human tissues. Clin Cancer Res . 1997;3:81–85.
de Galiza Barbosa F, Queiroz MA, Nunes RF, et al. Nonprostatic diseases on PSMA PET imaging: a spectrum of benign and malignant findings. Cancer Imaging . 2020;20:23.
Wiemels J, Wrensch M, Claus EB. Epidemiology and etiology of meningioma. J Neurooncol . 2010;99:307–314.
Zhang H, Rödiger LA, Shen T, et al. Perfusion MR imaging for differentiation of benign and malignant meningiomas. Neuroradiology . 2008;50:525–530.
Nagar VA, Ye JR, Ng WH, et al. Diffusion-weighted MR imaging: diagnosing atypical or malignant meningiomas and detecting tumor dedifferentiation. AJNR Am J Neuroradiol . 2008;29:1147–1152.
Bilgin R, Ergül N, Çermik TF. Incidental meningioma mimicking metastasis of prostate adenocarcinoma in 68 Ga-Labeled PSMA ligand PET/CT. Clin Nucl Med . 2016;41:956–958.
Sasikumar A, Joy A, Pillai MR, et al. Diagnostic value of 68 Ga PSMA-11 PET/CT imaging of brain tumors—preliminary analysis. Clin Nucl Med . 2017;42:e41–e48.
Gupta N, Verma R, Belho ES. Prostate-specific membrane antigen-avid meningioma detected in 68 Ga-prostate-specific membrane antigen PET/CT. Clin Nucl Med . 2020;45:692–693.
Junqueira MZ, Rocha NH, Sapienza MT. 68 Ga-prostate-specific membrane antigen PET/CT uptake in intraventricular meningioma in the choroid plexus. Clin Nucl Med . 2021;46:58–59.