Mortality following workplace injury: Quantitative bias analysis.
Confounding
Epidemiological bias
Excess mortality
Occupational Safety
Quantitative bias analysis
Journal
Annals of epidemiology
ISSN: 1873-2585
Titre abrégé: Ann Epidemiol
Pays: United States
ID NLM: 9100013
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
23
04
2021
revised:
17
09
2021
accepted:
23
09
2021
pubmed:
5
10
2021
medline:
15
12
2021
entrez:
4
10
2021
Statut:
ppublish
Résumé
Recent studies have shown increased all-cause mortality among workers following disabling workplace injury. These studies did not account for 2 potentially important confounders, smoking and obesity. We estimated injury-related mortality accounting for these factors. We followed workers receiving New Mexico workers' compensation benefits (1994-2000) through 2013. Using data from the Panel Study of Income Dynamics, we derived the joint distribution of smoking status and obesity for workers with and without lost-time injuries. We conducted a quantitative bias analysis (QBA) to determine the adjusted relationship of injury and mortality. We observed hazard ratios after adjusting for smoking and obesity of 1.13 for women (95% simulation interval (SI) 0.97 to 1.31) and 1.12 for men (95% SI 1.00 to 1.27). The estimated fully adjusted excess hazard was about half the estimates not adjusted for these factors. Using QBA to adjust for smoking and obesity reduced the estimated mortality hazard from lost-time injuries and widened the simulation interval. The adjusted estimate still showed more than a 10 percent increase for both women and men. The change in estimates reveals the importance of accounting for these confounders. Of course, the results depend on the methods and assumptions used.
Identifiants
pubmed: 34607011
pii: S1047-2797(21)00307-0
doi: 10.1016/j.annepidem.2021.09.015
pmc: PMC10026009
mid: NIHMS1879039
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
155-160Subventions
Organisme : Intramural CDC HHS
ID : CC999999
Pays : United States
Organisme : NIOSH CDC HHS
ID : R01 OH011511
Pays : United States
Organisme : NIOSH CDC HHS
ID : R21 OH010555
Pays : United States
Informations de copyright
Copyright © 2021. Published by Elsevier Inc.
Références
Soc Secur Bull. 2003-2004;65(4):31-7
pubmed: 16402660
PLoS Med. 2009 Apr 28;6(4):e1000058
pubmed: 19399161
Am J Public Health. 1992 Jan;82(1):29-32
pubmed: 1536330
Am J Ind Med. 2020 Oct;63(10):868-877
pubmed: 32677121
Annu Rev Public Health. 2005;26:239-57
pubmed: 15760288
Int J Occup Environ Health. 2015;21(2):142-50
pubmed: 25816923
Prev Med. 1994 Jul;23(4):515-20
pubmed: 7971880
Natl Vital Stat Rep. 2019 Jun;68(6):1-77
pubmed: 32501203
Am J Ind Med. 2016 Feb;59(2):106-18
pubmed: 26771100
Arch Intern Med. 2005 Oct 10;165(18):2122-8
pubmed: 16217002
Ann Epidemiol. 2015 Aug;25(8):575-582.e1
pubmed: 26066536
Can J Public Health. 2014 Jul 11;105(5):e330-5
pubmed: 25365266
Am J Ind Med. 2016 Dec;59(12):1061-1069
pubmed: 27427538
BMJ Open. 2016 Feb 25;6(2):e009232
pubmed: 26916688
Soc Secur Bull. 2012;72(3):1-17
pubmed: 23113426
Longit Life Course Stud. 2012;3(2):
pubmed: 23482334
Am J Ind Med. 2014 Oct;57(10):1165-73
pubmed: 25223516
Occup Environ Med. 2020 Sep;77(9):648-653
pubmed: 32332060
MMWR Suppl. 2014 Oct 31;63(4):3-27
pubmed: 25356673
Int J Epidemiol. 1996 Dec;25(6):1107-16
pubmed: 9027513
Am J Health Promot. 2007 May-Jun;21(5):460-8
pubmed: 17515011
J Occup Environ Med. 2012 Sep;54(9):1086-91
pubmed: 22929794
Am J Ind Med. 2020 Mar;63(3):209-217
pubmed: 31833089
Am J Ind Med. 1999 Nov;36(5):487-503
pubmed: 10506731
BMC Public Health. 2013 Apr 05;13:303
pubmed: 23560685
Am J Epidemiol. 2007 Jul 15;166(2):204-11
pubmed: 17485732