Retrospective evaluation of the relationship between admission variables and brain herniation in dogs (2010-2019): 54 cases.
Cushing reflex
Cushing response
brain herniation
canine
modified Glasgow coma scale
Journal
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
ISSN: 1476-4431
Titre abrégé: J Vet Emerg Crit Care (San Antonio)
Pays: United States
ID NLM: 101152804
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
revised:
09
06
2020
received:
20
10
2019
accepted:
21
07
2020
pubmed:
6
10
2021
medline:
2
2
2022
entrez:
5
10
2021
Statut:
ppublish
Résumé
To document the admission systolic blood pressure (SBP), heart rate (HR), and modified Glasgow coma scale (MGCS) score in dogs with and without brain herniation and to determine their relationship with brain herniation. Retrospective study between 2010 and 2019. University veterinary teaching hospital. Fifty-four client-owned dogs with brain herniation and 40 client-owned dogs as a control group, as determined on magnetic resonance imaging. None. SBP, HR, MGCS score, and outcome were extracted from medical records. MGCS score was retrospectively calculated based on initial neurological examination in dogs with adequate available information. Dogs with brain herniation had a significantly higher SBP (P = 0.0078), greater SBP-HR difference (P = 0.0006), and lower MGCS score (P < 0.0001) compared to control dogs. A cutoff value of an SBP ≥ 178 mm Hg, SBP-HR ≥ 60, and MGCS score ≤ 14 each provides a specificity of 90%-98%. A combination of an SBP > 140 mm Hg and HR < 80/min provided 24% sensitivity and 100% specificity to diagnose dogs with brain herniation (P < 0.0001). A high SBP, a greater difference between SBP and HR, a combination of higher SBP and lower HR, and a low MGCS score were associated with brain herniation in dogs presenting with neurological signs upon admission. Early recognition of these abnormalities may help veterinarians to suspect brain herniation and determine timely treatment.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
50-57Informations de copyright
© Veterinary Emergency and Critical Care Society 2021.
Références
Walmsley GL, Herrtage ME, Dennis R, Platt SR, Jeffery ND. The relationship between clinical signs and brain herniation associated with rostrotentorial mass lesions in the dog. Vet J. 2006;172(2):258-264.
Platt SR, Garosi LS. Head trauma. Small Animal Neurological Emergencies. CRC Press, Taylor & Francis Group; 2012.
Stevens RD, Shoykhet M, Cadena R. Emergency neurological life support: intracranial hypertension and herniation. Neurocrit Care. 2015;23:76-82.
Lewis MJ, Olby NJ, Early PJ, et al. Clinical and diagnostic imaging features of brain herniation in dogs and cats. J Vet Intern Med. 2016;30(5):1672-1680.
Kornegay JN, Oliver JE, Gorgacz EJ. Clinicopathologic features of brain herniation in animals. J Am Vet Med Assoc. 1983;182(10):1111-1116.
Bagley RS. Pathophysiologic sequelae of intracranial disease. Vet Clin North Am Small Anim Pract. 1996;26(4):711-733.
Squire LR, ed. Brain Herniation Types. 1st ed. Academic Press Inc; 2009.
Rodney SB. Pathophysiologic sequelae of intracranial disease. Vet Clin North Am Small Anim Pract. 2015;26(4):711-733.
Koenig MA, Bryan M, Lewin JL, Mirski MA, Geocadin RG, Stevens RD. Reversal of transtentorial herniation with hypertonic saline. Neurology. 2008;70:(13):1023-1029. https://doi.org/10.1212/01.wnl.0000304042.05557.60
Fodstad H, Kelly PJ, Buchfelder M. History of the Cushing reflex. Neurosurgery. 2006;59(5):1132-1137.
Dewey CW, da Costa RC, eds. Lesion Localization. Practical Guide to Canine and Feline Neurology. 3rd ed. Wiley Blackwell; 2016.
Steiner L, Löfgren J, Zwetnow NN. Lethal mechanism in repeated subarachnoid hemorrhage in dogs. Acta Neurol Scand. 1975;52(4):268-293.
Fallis A. Clinicopathologic features of intracranial central neurocytomas in 2 dogs. J Vet Intern Med. 2012;26:186-191.
Heymans C. The control of heart rate consequent to changes in the cephalic blood pressure and in the intracranial pressure. Am J Physiol. 1928;85:498-505.
Yumoto T, Mitsuhashi T, Yamakawa Y, et al. Impact of Cushing's sign in the prehospital setting on predicting the need for immediate neurosurgical intervention in trauma patients: a nationwide retrospective observational study. Scand J Trauma Resusc Emerg Med. 2016;24(1):2-5.
Yumoto T, Naito H, Yorifuji T, et al. Cushing's sign and severe traumatic brain injury in children after blunt trauma: a nationwide retrospective cohort study in Japan. BMJ Open. 2018;8(3):1-7.
Kalmar AF, Van Aken J, Caemaert J, Mortier EP, Struys MMRF. Value of Cushing reflex as warning sign for brain ischaemia during neuroendoscopy. Br J Anaesth. 2005;94(6):791-799.
Platt SR, Radaelli ST, McDonnell JJ. The prognostic value of the modified Glasgow coma scale in head trauma in dogs. J Vet Intern Med. 2001;15(6):581-584.
Beltran E, Platt SR, McConnell JF, Dennis R, Keys DA, De Risio L. Prognostic value of early magnetic resonance imaging in dogs after traumatic brain injury: 50 cases. J Vet Intern Med. 2014;28(4):1256-1262.
Bellis T, Daly M, Davidson B. Central diabetes insipidus following cardiopulmonary arrest in a dog. J Vet Emerg Crit Care. 2015;25(6):745-750.
Sharma D, Holowaychuk MK. Retrospective evaluation of prognostic indicators in dogs with head trauma: 72 cases (January-March 2011). J Vet Emerg Crit Care. 2015;25(5):631-639.
Boller M, Fletcher DJ, Brainard BM, et al. Utstein-style guidelines on uniform reporting of in-hospital cardiopulmonary resuscitation in dogs and cats. A RECOVER statement. J Vet Emerg Crit Care. 2016;26(1):11-34.
Kalita J, Misra UK, Vajpeyee A, Phadke RV, Handique A, Salwani V. Brain herniations in patients with intracerebral hemorrhage. Acta Neurol Scand. 2009;119(4):254-260.