No evidence for colonization of oral bacteria in the distal gut in healthy adults.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
19 10 2021
Historique:
accepted: 13 09 2021
entrez: 6 10 2021
pubmed: 7 10 2021
medline: 21 12 2021
Statut: ppublish

Résumé

The microbial communities in the mouth and colon are anatomically connected via the saliva. However, the extent to which oral microbes reach and successfully colonize the distal gut has been debated. To resolve this long-standing controversy, we used exact amplicon sequence variants generated from concurrently collected saliva/stool microbiota in 66 healthy adults from two countries to show that, with one exception (

Identifiants

pubmed: 34610963
pii: 2114152118
doi: 10.1073/pnas.2114152118
pmc: PMC8594488
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NCATS NIH HHS
ID : KL2 TR002492
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 the Author(s). Published by PNAS.

Déclaration de conflit d'intérêts

The authors declare no competing interest.

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Auteurs

Armin Rashidi (A)

Department of Medicine, University of Minnesota, Minneapolis, MN 55455; arashidi@umn.edu.

Maryam Ebadi (M)

Department of Medicine, University of Minnesota, Minneapolis, MN 55455.

Daniel J Weisdorf (DJ)

Department of Medicine, University of Minnesota, Minneapolis, MN 55455.

Massimo Costalonga (M)

School of Dentistry, University of Minnesota, Minneapolis, MN 55455.

Christopher Staley (C)

Department of Surgery, University of Minnesota, Minneapolis, MN 55455.

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Classifications MeSH