Temporal Trends in Post Myocardial Infarction Heart Failure and Outcomes Among Older Adults.


Journal

Journal of cardiac failure
ISSN: 1532-8414
Titre abrégé: J Card Fail
Pays: United States
ID NLM: 9442138

Informations de publication

Date de publication:
04 2022
Historique:
received: 13 06 2021
revised: 01 09 2021
accepted: 01 09 2021
pubmed: 9 10 2021
medline: 20 4 2022
entrez: 8 10 2021
Statut: ppublish

Résumé

We sought to determine national trends and long term outcomes of post myocardial infarction (MI) heart failure. An MI can be complicated by heart failure; there are limited data describing the contemporary patterns and clinical implications of post-MI heart failure. We studied patients with an MI aged 65 years or older from 2000 to 2013 in a Medicare database. New-onset heart failure after an MI was defined as either heart failure during the index MI admission or a hospitalization for heart failure within 1 year of the index MI event. A trend analysis of the incidence of heart failure was performed, and differences were examined by Gray tests. The 5-year mortality rates were evaluated and differences among heart failure cohorts were ascertained by Gray tests. There were a total of 1,531,638 patients with an MI and 565,291 patients had heart failure (36.0%). The rate of heart failure during index admission was 32.3% and the frequency of heart failure hospitalization within 1 year was 10.4%. Patients with heart failure were older (81 years vs 77 years). The temporal trend from 2001 to 2012 suggested a decrease in the incidence of heart failure during index admission (2001: 34.7%, 2012: 31.2%, P Post-MI heart failure in older adults occurs in 1 in 3 patients within 1 year; heart failure portends significantly higher long-term mortality.

Sections du résumé

BACKGROUND
We sought to determine national trends and long term outcomes of post myocardial infarction (MI) heart failure. An MI can be complicated by heart failure; there are limited data describing the contemporary patterns and clinical implications of post-MI heart failure.
METHODS AND RESULTS
We studied patients with an MI aged 65 years or older from 2000 to 2013 in a Medicare database. New-onset heart failure after an MI was defined as either heart failure during the index MI admission or a hospitalization for heart failure within 1 year of the index MI event. A trend analysis of the incidence of heart failure was performed, and differences were examined by Gray tests. The 5-year mortality rates were evaluated and differences among heart failure cohorts were ascertained by Gray tests. There were a total of 1,531,638 patients with an MI and 565,291 patients had heart failure (36.0%). The rate of heart failure during index admission was 32.3% and the frequency of heart failure hospitalization within 1 year was 10.4%. Patients with heart failure were older (81 years vs 77 years). The temporal trend from 2001 to 2012 suggested a decrease in the incidence of heart failure during index admission (2001: 34.7%, 2012: 31.2%, P
CONCLUSIONS
Post-MI heart failure in older adults occurs in 1 in 3 patients within 1 year; heart failure portends significantly higher long-term mortality.

Identifiants

pubmed: 34624511
pii: S1071-9164(21)00361-4
doi: 10.1016/j.cardfail.2021.09.001
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

531-539

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Ajar Kochar (A)

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address: akochar@bwh.harvard.edu.

Jacob A Doll (JA)

Section of Cardiology, VA Puget Sound Health Care System, Seattle, Washington; Division of Cardiology, University of Washington, Seattle, Washington.

Li Liang (L)

Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.

Jerry Curran (J)

Abiomed Inc., Danvers, Massachusetts.

Eric D Peterson (ED)

Office of the Provost, Department of Internal Medicine, University of Texas Southwestern, Medical Center, Dallas, Texas.

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