The harmless acute pancreatitis score (HAPS) identifies non-severe patients: A systematic review and meta-analysis.

Acute pancreatitis Harmless acute pancreatitis score (HAPS) Meta-analysis Predictor

Journal

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
ISSN: 1424-3911
Titre abrégé: Pancreatology
Pays: Switzerland
ID NLM: 100966936

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 24 08 2021
revised: 28 09 2021
accepted: 30 09 2021
pubmed: 12 10 2021
medline: 1 3 2022
entrez: 11 10 2021
Statut: ppublish

Résumé

We previously described a scoring system to identify patients with harmless acute pancreatitis as defined by absence of pancreatic necrosis, no need for artificial ventilation or dialysis, and non-fatal course. This scoring system, the Harmless Acute Pancreatitis Score (HAPS), can be quickly calculated from three parameters: absence of abdominal tenderness or rebound, normal hematocrit and normal creatinine level. We aim to assess the positive predictive value (PPV) of the HAPS by performing a meta-analysis of subsequently published studies. We performed a literature search using Pubmed, Web of Science Twenty reports covering 6374 patients were identified. The overall PPV based on 16 studies that closely followed the original description of the HAPS system was 97% (95%CI 95-99%) with significant heterogeneity (I The HAPS, if used as originally defined, accurately identifies patients with non-severe AP who will not require ICU care and facilitate selection of patients who can be discharged after a short stay on a general ward or can even be cared for at home. This could free hospital beds for other purposes and decrease healthcare costs.

Identifiants

pubmed: 34629293
pii: S1424-3903(21)00581-0
doi: 10.1016/j.pan.2021.09.017
pii:
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1419-1427

Informations de copyright

Copyright © 2021 IAP and EPC. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no conflict of interest.

Auteurs

Patrick Maisonneuve (P)

Chief, Unit of Clinical Epidemiology, Division of Epidemiology and Biostatistics, IEO, European Institute of Oncology IRCCS, Milan, Italy. Electronic address: patrick.maisonneuve@ieo.it.

Albert B Lowenfels (AB)

Emeritus Professor of Surgery and Professor of Family Medicine New York Medical College, Valhalla, NY, USA. Electronic address: Al_Lowenfels@nymc.edu.

Paul G Lankisch (PG)

Retired Chief of Department of General Internal Medicine and Gastroenterology, Clinical Centre of Lüneburg, Lüneburg, Germany. Electronic address: paulgeorg.lankisch@t-online.de.

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Classifications MeSH