questionsmedicales.fr
Maladies de l'appareil digestif
Maladies du pancréas
Pancréatite
Pancréatite aigüe nécrotique
Pancréatite aigüe nécrotique : Questions médicales fréquentes
Diagnostic
5
Pancréatite
Imagerie médicale
Échographie
Tomodensitométrie
Douleur abdominale
Choc hypovolémique
Score de Ranson
Score APACHE II
Symptômes
5
Douleur abdominale
Nausées
Jaunisse
Obstruction des voies biliaires
Douleur épigastrique
Douleur abdominale
Vomissements
Déshydratation
Prévention
5
Tabagisme
Facteurs de risque
Hyperlipidémie
Maladies métaboliques
Calculs biliaires
Prévention
Traitements
5
Hydratation intraveineuse
Jeûne
Suivi médical
Fonction pancréatique
Complications
5
Infection
Insuffisance organique
Pseudokystes
Suivi médical
Insuffisance respiratoire
Insuffisance rénale
Traitement précoce
Prévention des complications
Facteurs de risque
5
Alcoolisme
Antécédents familiaux
Maladies auto-immunes
Facteurs de risque
Obésité
Facteurs de risque
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"name": "Les vomissements sont-ils fréquents ?",
"position": 10,
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{
"@type": "Question",
"name": "Le tabagisme est-il un facteur de risque ?",
"position": 12,
"acceptedAnswer": {
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}
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"position": 13,
"acceptedAnswer": {
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"@type": "Question",
"name": "Comment gérer les calculs biliaires ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un traitement préventif des calculs biliaires peut réduire le risque de pancréatite."
}
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"@type": "Question",
"name": "L'alimentation joue-t-elle un rôle ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en graisses peut augmenter le risque de pancréatite aigüe."
}
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"@type": "Question",
"name": "Quel est le traitement principal ?",
"position": 16,
"acceptedAnswer": {
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"text": "Le traitement consiste en une hospitalisation, une hydratation intraveineuse et un jeûne."
}
},
{
"@type": "Question",
"name": "Des antibiotiques sont-ils nécessaires ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antibiotiques sont prescrits si une infection est suspectée ou confirmée."
}
},
{
"@type": "Question",
"name": "Quand une intervention chirurgicale est-elle nécessaire ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une chirurgie est envisagée en cas de complications comme des abcès ou des nécroses étendues."
}
},
{
"@type": "Question",
"name": "Comment gérer la douleur ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des analgésiques puissants, comme les opioïdes, sont souvent utilisés pour soulager la douleur."
}
},
{
"@type": "Question",
"name": "Quel suivi est nécessaire après traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi régulier est essentiel pour surveiller les complications et la fonction pancréatique."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent l'infection, l'insuffisance organique et les pseudokystes."
}
},
{
"@type": "Question",
"name": "Les pseudokystes sont-ils fréquents ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les pseudokystes peuvent se former après une pancréatite aigüe et nécessiter un suivi."
}
},
{
"@type": "Question",
"name": "Comment l'insuffisance organique se manifeste-t-elle ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut se manifester par des défaillances respiratoires, rénales ou cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Les complications augmentent-elles le risque de mortalité ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications graves peuvent significativement augmenter le risque de mortalité."
}
},
{
"@type": "Question",
"name": "Comment prévenir les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un traitement précoce et approprié de la pancréatite peut réduire le risque de complications."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les principaux facteurs incluent l'alcoolisme, les calculs biliaires et les antécédents familiaux."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque de pancréatite augmente avec l'âge, surtout après 50 ans."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils être un facteur ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments, comme les diurétiques, peuvent augmenter le risque de pancréatite."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes sont-elles liées ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies auto-immunes peuvent prédisposer à la pancréatite aigüe."
}
},
{
"@type": "Question",
"name": "Le surpoids est-il un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité est un facteur de risque reconnu pour le développement de la pancréatite."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 09/01/2026
Contenu vérifié selon les dernières recommandations médicales
7 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Department of Critical Care Medicine, Jinling Hospital, Medical College of Nanjing University, Nanjing, Jiangsu, China.
National Institute of Healthcare Data Science, Nanjing University, Nanjing, Jiangsu, China.
7 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Department of Critical Care Medicine, Jinling Hospital, Medical College of Nanjing University, Nanjing, Jiangsu, China.
National Institute of Healthcare Data Science, Nanjing University, Nanjing, Jiangsu, China.
6 publications dans cette catégorie
Affiliations :
Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India. -Pankajgupta959@gmail.com.
6 publications dans cette catégorie
Affiliations :
Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
6 publications dans cette catégorie
Affiliations :
Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
5 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Department of Critical Care Medicine, Jinling Hospital, Medical College of Nanjing University, Nanjing, Jiangsu, China.
National Institute of Healthcare Data Science, Nanjing University, Nanjing, Jiangsu, China.
Publications dans "Pancréatite aigüe nécrotique" :
5 publications dans cette catégorie
Affiliations :
Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Publications dans "Pancréatite aigüe nécrotique" :
5 publications dans cette catégorie
Affiliations :
Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Publications dans "Pancréatite aigüe nécrotique" :
4 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Department of Critical Care Medicine, Jinling Hospital, Medical College of Nanjing University, Nanjing, Jiangsu, China.
National Institute of Healthcare Data Science, Nanjing University, Nanjing, Jiangsu, China.
Publications dans "Pancréatite aigüe nécrotique" :
4 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Department of Critical Care Medicine, Jinling Hospital, Medical College of Nanjing University, Nanjing, Jiangsu, China.
National Institute of Healthcare Data Science, Nanjing University, Nanjing, Jiangsu, China.
Publications dans "Pancréatite aigüe nécrotique" :
4 publications dans cette catégorie
Affiliations :
Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Publications dans "Pancréatite aigüe nécrotique" :
4 publications dans cette catégorie
Affiliations :
Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Publications dans "Pancréatite aigüe nécrotique" :
4 publications dans cette catégorie
Affiliations :
Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr., EH 519, Indianapolis, IN, 46202, USA.
Publications dans "Pancréatite aigüe nécrotique" :
4 publications dans cette catégorie
Affiliations :
Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr., EH 519, Indianapolis, IN, 46202, USA. nzyromsk@iupui.edu.
Publications dans "Pancréatite aigüe nécrotique" :
3 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Department of Critical Care Medicine, Jinling Hospital, Medical College of Nanjing University, Nanjing, Jiangsu, China.
National Institute of Healthcare Data Science, Nanjing University, Nanjing, Jiangsu, China.
Publications dans "Pancréatite aigüe nécrotique" :
3 publications dans cette catégorie
Affiliations :
Department of Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Department of Critical Care Medicine, Jinling Hospital, Medical College of Nanjing University, Nanjing, Jiangsu, China.
National Institute of Healthcare Data Science, Nanjing University, Nanjing, Jiangsu, China.
Publications dans "Pancréatite aigüe nécrotique" :
3 publications dans cette catégorie
Affiliations :
Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.
Publications dans "Pancréatite aigüe nécrotique" :
3 publications dans cette catégorie
Affiliations :
BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
Publications dans "Pancréatite aigüe nécrotique" :
3 publications dans cette catégorie
Affiliations :
BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
Publications dans "Pancréatite aigüe nécrotique" :
3 publications dans cette catégorie
Affiliations :
BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
Publications dans "Pancréatite aigüe nécrotique" :
It is recommended to drain the pancreatic fluid collections later in the course of the acute necrotizing pancreatitis (ANP). However, earlier drainage may be indicated. We compared early (≤ 2 weeks) v...
This retrospective study comprised ANP patients who underwent PCD of ANC. The diagnosis of ANP was based on revised Atlanta classification criteria and computed tomography performed between 5 and 7 da...
One hundred forty-eight patients (74 in each group) were evaluated. The procedures were technically successful in all patients. The clinical success rate was 67.6% in group I vs. 77% in group II (p = ...
Early PCD is as technically successful as late PCD in the management of ANC. However, early PCD is associated with higher surgical rate and higher incidence of complications....
Peripheral absolute lymphocyte count (ALC) has the potential to predict infected pancreatic necrosis (IPN), but requires verification. This study aimed to assess whether early mean absolute lymphocyte...
The study subjects are from the TRACE trial and a single-center cohort study. ALC during the first seven days was used to define early mean ALC. The entire cohort was then divided into quartiles of ea...
A total of 660 patients (median age, 44 years; 63.8 % males) were included and 157 (23.8 %) developed IPN within a 90-day period. The median (interquartile range, IQR) of the early mean ALC is 1.07 (0...
Among patients with ANP, early mean ALC was significantly associated with the development of IPN. Preventive strategies should be considered in patients with reduced ALC....
Acute necrotizing pancreatitis (ANP) complicates up to 15% of acute pancreatitis cases. ANP has historically been associated with a significant risk for readmission, but there are currently no studies...
We performed a retrospective review of all consecutive patients presenting to hospitals in the Indiana University (IU) Health system with pancreatic necrosis between December 2016 and June 2020. Patie...
One hundred and sixty-two patients met study criteria. 27.7% of the cohort was readmitted within 30-days of index discharge. The median time to readmission was 10 days (IQR 5-17 days). The most freque...
Patients with ANP have a significant risk for early (<30 days) readmission. Direct discharge to home, rather than short or long-term rehabilitation facilities, is associated with lower odds of early r...
Outcomes from some recent clinical trials have helped to improve the management of necrotizing pancreatitis over the last 2 decades. The location of the retroperitoneal collection, previous gastric su...
Involvement of transverse mesocolon (TM) during acute necrotizing pancreatitis(ANP) indicates that inflammation has spread from retroperitoneal space to peritoneum. Nevertheless, the impact of TM invo...
This study aimed to explore the association between CECT-diagnosed TM involvement and the development of colonic fistula in a cohort of ANP patients....
This is a single-center, retrospective cohort study involving ANP patients admitted from January 2020 to December 2020. TM involvement was diagnosed by two experienced radiologists. The study subjects...
A total of 180 patients with ANP were enrolled, and 86 (47.8%) patients had TM involvement. The incidence of the colonic fistula is significantly higher in patients with TM involvement (16.3% vs. 5.3%...
TM involvement in ANP patients is associated with development of colonic fistula in ANP patients....
Acute pancreatitis is a common diagnosis which requires a prompt diagnosis and management by a multidisciplinary team with often general surgeons as the initial provider. Morbidity and mortality from ...
In this review paper, we discuss all aspects of acute pancreatitis and its potential complications, as well providing updates in the modern management of necrotizing pancreatitis. Practicing general s...
We conducted a review of literature of evidence and management options for acute pancreatitis, including all published manuscripts from 2012 to 2022....
Diagnosis and management of this disease can vary among specialiaties. The decision to utilize a percutaneous or endoscopic techniques are relevant points of discussion within general surgery and gast...
Acute pancreatitis is a disease which requires multidisciplinary approach with evolving treatment options to less invasive nonsurgical methods....
Nowadays, minimally invasive intervention (MII) has largely replaced delayed open surgery in acute necrotizing pancreatitis (ANP). However, the timing of MII remains unclear. The present study investi...
Studies evaluating the impact of the timing of MII on complications in ANP patients were thoroughly searched on PubMed, Embase, Cochrane Library, and Web of Science from inception to June 2022. The pr...
Nine studies reporting 870 patients undergoing MII for ANP were included. No significant difference was found in mortality between the early and delayed intervention groups. In addition, the timing of...
Early intervention is safe and recommended only for patients with indications for intervention, such as infection....
Pancreatic fluid collections (PFCs) typically develop as local complications of acute pancreatitis and complicate the clinical course of patients with acute pancreatitis and potentially fatal clinical...
Postponed open necrosectomy or minimally invasive intervention has become the treatment option for necrotizing pancreatitis. Nevertheless, several studies point to the safety and efficacy of early int...
Literature search was performed in multiple databases for articles that compared the safety and clinical outcomes of early (<4 weeks from the onset of pancreatitis) versus late intervention (≥4 weeks ...
Fourteen studies were included in the final analysis. For open necrosectomy intervention, the overall pooled OR of mortality rate with the late intervention compared with early intervention was 7.09 (...
These results showed the benefit of late interventions in patients with necrotizing pancreatitis in both minimally invasive procedures and open necrosectomy. Late intervention is preferred in the mana...
For infected necrotizing pancreatitis (INP), percutaneous catheter drainage (PCD) is now widely acknowledged as the initial intervention in a step-up approach, followed, if necessary, by minimally inv...
In an observational study conducted between April 2015 and December 2020, PCD was utilized as the initial step to treat 143 consecutive INP patients. A surgical necrosectomy was performed when the pat...
In 62 (43.4%) patients, PCD was successful, while the remaining 81 (56.6%) individuals required subsequent surgical necrosectomy. In the multivariate model, organ failure, percentage of pancreatic nec...
A risk score model integrating organ failure, percentage of pancreatic necrosis, extrapancreatic necrosis volume, and mean CT density of extrapancreatic necrosis volume can identify INP patients at hi...