Cardiopulmonary reserve examined with cardiopulmonary exercise testing in individuals with chronic kidney disease: A systematic review and meta-analysis.

CPET Cardiopulmonary exercise testing Cardiovascular reserve Chronic kidney disease Exercise intolerance VO2peak

Journal

Annals of physical and rehabilitation medicine
ISSN: 1877-0665
Titre abrégé: Ann Phys Rehabil Med
Pays: Netherlands
ID NLM: 101502773

Informations de publication

Date de publication:
Sep 2022
Historique:
received: 23 01 2021
revised: 31 05 2021
accepted: 15 06 2021
pubmed: 12 10 2021
medline: 31 8 2022
entrez: 11 10 2021
Statut: ppublish

Résumé

Patients with chronic kidney disease (CKD) often present reduced physical activity and exercise tolerance due to factors relevant to co-existing disturbances of the cardiac, nervous and muscular systems. Cardiopulmonary exercise testing (CPET) is used for clinical evaluation of exercise limitation and related symptoms (i.e., dyspnea, fatigue) in several medical fields. This is a systematic review and meta-analysis of studies using CPET technology to examine cardiopulmonary reserve in individuals with versus without CKD. Literature search involved PubMed, Web of Science and Scopus databases; manual search of article references and of gray literature was also performed. Observational studies and randomized trials that used CPET for patients with CKD stage 1-5 versus controls were eligible. The primary outcome was peak oxygen uptake (VO From an initial 4944 literature records, we identified 29 studies fulfilling the inclusion criteria; of these, 25 studies (2,213 participants) with complete data were included in the final meta-analysis. VO VO CRD42021227805.

Sections du résumé

BACKGROUND BACKGROUND
Patients with chronic kidney disease (CKD) often present reduced physical activity and exercise tolerance due to factors relevant to co-existing disturbances of the cardiac, nervous and muscular systems. Cardiopulmonary exercise testing (CPET) is used for clinical evaluation of exercise limitation and related symptoms (i.e., dyspnea, fatigue) in several medical fields.
OBJECTIVES OBJECTIVE
This is a systematic review and meta-analysis of studies using CPET technology to examine cardiopulmonary reserve in individuals with versus without CKD.
METHODS METHODS
Literature search involved PubMed, Web of Science and Scopus databases; manual search of article references and of gray literature was also performed. Observational studies and randomized trials that used CPET for patients with CKD stage 1-5 versus controls were eligible. The primary outcome was peak oxygen uptake (VO
RESULTS RESULTS
From an initial 4944 literature records, we identified 29 studies fulfilling the inclusion criteria; of these, 25 studies (2,213 participants) with complete data were included in the final meta-analysis. VO
CONCLUSIONS CONCLUSIONS
VO
PROSPERO REGISTRATION NUMBER UNASSIGNED
CRD42021227805.

Identifiants

pubmed: 34634515
pii: S1877-0657(21)00106-8
doi: 10.1016/j.rehab.2021.101588
pii:
doi:

Types de publication

Journal Article Meta-Analysis Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

101588

Informations de copyright

Copyright © 2021 Elsevier Masson SAS. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest None declared.

Auteurs

Eva Pella (E)

Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Greece.

Marieta P Theodorakopoulou (MP)

Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Greece.

Afroditi K Boutou (AK)

Department of Respiratory Medicine, G. Papanikolaou Hospital, Thessaloniki, Greece.

Maria-Eleni Alexandrou (ME)

Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Greece.

Dimitra-Rafailia Bakaloudi (DR)

Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Greece.

Despoina Sarridou (D)

Department of Cardiothoracic and Vascular Anaesthesia, G. Papanikolaou Hospital, Thessaloniki, Greece.

Aristi Boulmpou (A)

Third Department of Cardiology, Hippokration University Hospital, Aristotle University of Thessaloniki, Greece.

Christodoulos Papadopoulos (C)

Third Department of Cardiology, Hippokration University Hospital, Aristotle University of Thessaloniki, Greece.

Aikaterini Papagianni (A)

Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Greece.

Pantelis Sarafidis (P)

Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Greece. Electronic address: psarafidis@auth.gr.

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Classifications MeSH