Transcriptional Regulation of the Human IL5RA Gene through Alternative Promoter Usage during Eosinophil Development.

Antigens, CD34 / genetics Base Sequence CCAAT-Enhancer-Binding Proteins / genetics Cell Differentiation / genetics Cells, Cultured Eosinophils / physiology Gene Expression Regulation / genetics Hematopoietic Stem Cells / physiology Humans Interleukin-5 Receptor alpha Subunit / genetics Promoter Regions, Genetic / genetics Protein Isoforms / genetics RNA, Messenger / genetics Transcription Factors / genetics Transcription, Genetic / genetics
IL-5RA expression alternative promoters eosinophil development

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
23 Sep 2021
Historique:
received: 23 08 2021
revised: 20 09 2021
accepted: 20 09 2021
entrez: 13 10 2021
pubmed: 14 10 2021
medline: 29 10 2021
Statut: epublish

Résumé

Regulation of the IL-5 receptor alpha (

Identifiants

DOI: 10.3390/ijms221910245 PMID: 34638583 PMC: PMC8549700
pubmed: 34638583
pii: ijms221910245
doi: 10.3390/ijms221910245
pmc: PMC8549700
pii:
doi:

Substances chimiques

Antigens, CD34 0
CCAAT-Enhancer-Binding Proteins 0
IL5RA protein, human 0
Interleukin-5 Receptor alpha Subunit 0
Protein Isoforms 0
RNA, Messenger 0
Transcription Factors 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Institute of Allergy and Infectious Diseases
ID : AI033043

Références

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Auteurs

Kimberly G Laffey (KG)

Department of Biochemistry and Molecular Genetics (M/C 669), College of Medicine, University of Illinois at Chicago, 2074 Molecular Biology Research Building, 900 S. Ashland Ave., Chicago, IL 60607, USA.
Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.

Jian Du (J)

Department of Biochemistry and Molecular Genetics (M/C 669), College of Medicine, University of Illinois at Chicago, 2074 Molecular Biology Research Building, 900 S. Ashland Ave., Chicago, IL 60607, USA.

Adam G Schrum (AG)

Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Department of Surgery, School of Medicine, University of Missouri, Columbia, MO 65212, USA.
Department of Biomedical, Biological, and Chemical Engineering, College of Engineering, University of Missouri, Columbia, MO 65211, USA.

Steven J Ackerman (SJ)

Department of Biochemistry and Molecular Genetics (M/C 669), College of Medicine, University of Illinois at Chicago, 2074 Molecular Biology Research Building, 900 S. Ashland Ave., Chicago, IL 60607, USA.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Antigènes de différenciation › Antigènes CD › Antigènes CD34 › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence nucléotidique › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique et à glissière à leucines › Protéines liant les séquences stimulatrices de type CCAAT › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Cellules › Cellules cultivées › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Granulocytes › Granulocytes éosinophiles › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système hématopoïétique › Cellules de la moelle osseuse › Cellules souches hématopoïétiques › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux interleukines › Récepteurs à l'interleukine-5 › Sous-unité alpha du récepteur à l'interleukine-5 › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Éléments de régulation transcriptionnelle › Régions promotrices (génétique) › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Isoformes de protéines › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN messager › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Transcriptional Regulation of the Human IL5RA...
questionsmedicales.fr › Phénomènes génétiques › Expression des gènes › Transcription génétique › Transcriptional Regulation of the Human IL5RA...