Prophylactic supplementation of phosphate, magnesium, and potassium for the prevention of refeeding syndrome in hospitalized individuals with anorexia nervosa.


Journal

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
ISSN: 1941-2452
Titre abrégé: Nutr Clin Pract
Pays: United States
ID NLM: 8606733

Informations de publication

Date de publication:
Apr 2022
Historique:
pubmed: 15 10 2021
medline: 22 3 2022
entrez: 14 10 2021
Statut: ppublish

Résumé

Medical stabilization, nutrition rehabilitation, and weight restoration, while minimizing risk for the potentially fatal complication of refeeding syndrome, are the primary goals for the treatment of hospitalized individuals with anorexia nervosa and other restrictive-type eating disorders. The purpose of this review was to examine the literature exploring the prophylactic supplementation of phosphate, magnesium, and potassium, in addition to routine thiamin and multivitamin supplementation, for the prevention of refeeding syndrome in adolescents and adults with anorexia nervosa. Through evaluation of outcomes (including serum electrolyte levels and clinical signs and symptoms such as respiratory failure, cardiac failure, peripheral edema, rhabdomyolysis, and encephalopathy), three studies found that prophylactic supplementation of potassium, magnesium, and/or phosphate were effective in preventing refeeding syndrome or refeeding hypophosphatemia (a characteristic of refeeding syndrome). Although all studies found that prophylactic supplementation was effective in preventing refeeding syndrome, refeeding approaches (including the method, amount, and duration of nutrient delivery) as well as the populations studied varied considerably, making it difficult to arrive at specific recommendations for practice. Randomized controlled trials are needed to further examine the safety and effectiveness of prophylactic supplementation of phosphate, magnesium, and potassium on the prevention of refeeding syndrome, utilizing similar feeding and supplementation protocols.

Identifiants

pubmed: 34648201
doi: 10.1002/ncp.10786
doi:

Substances chimiques

Phosphates 0
Magnesium I38ZP9992A
Potassium RWP5GA015D

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

328-343

Informations de copyright

© 2021 American Society for Parenteral and Enteral Nutrition.

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Auteurs

Donna Gallagher (D)

School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, Rutgers University, Highlands, New Jersey, USA.

Anna Parker (A)

School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, Rutgers University, Highlands, New Jersey, USA.

Hamed Samavat (H)

School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, Rutgers University, Highlands, New Jersey, USA.

Rena Zelig (R)

School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, Rutgers University, Highlands, New Jersey, USA.

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