Cardiovascular risk and stroke mortality in persons living with HIV: a longitudinal study in a hospital in Yaounde.
Adult
Aged
Anti-HIV Agents
/ administration & dosage
Cameroon
Cardiovascular Diseases
/ epidemiology
Cohort Studies
Female
HIV Infections
/ drug therapy
Heart Disease Risk Factors
Hospitalization
/ statistics & numerical data
Humans
Ischemic Stroke
/ epidemiology
Length of Stay
Longitudinal Studies
Male
Middle Aged
Retrospective Studies
Risk Factors
Stroke
/ epidemiology
Cameroon
Cardiovascular risk
HIV
death
stroke
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2021
2021
Historique:
received:
19
07
2021
accepted:
16
08
2021
entrez:
15
10
2021
pubmed:
16
10
2021
medline:
27
10
2021
Statut:
epublish
Résumé
HIV infection is a well-known risk factor for stroke, especially in young adults. In Cameroon, there is a death of data on the outcome of stroke among persons living with HIV (PLWH). This study aimed to assess the cardiovascular risk profile and mortality in PLWH who had a stroke. this was a retrospective cohort study of all PLWH aged ≥18 years admitted for stroke between January 2010 and December 2019 to the Cardiology Unit of the Yaoundé Central Hospital, Cameroon. Cardiovascular risk was estimated using the modified Framingham score, with subsequent dichotomization into low and intermediate/high risk. Mortality was assessed on day 7 during hospitalization (medical records), at one month, and one year by telephone call to a relative. a total of 43 PLWH who had a stroke were enrolled. Their mean age was 52.1 (standard deviation 12.9) years, most of them were female (69.8%, n = 30). There were 25 (58.1%) patients on concomitant antiretroviral therapy. The Framingham cardiovascular risk score at admission was low in 29 patients (67.4%) and intermediate to high in 14 patients (32.6%). Ischemic stroke was the most common type of stroke in 36 persons (83.7%). The length of hospital stay was 11.4 (interquartile range 9.2-13.7) days. Mortality at 1 year was 46.5% (n = 20). stroke mortality was high in this population of PLWH. Most patients had a low Framingham score, suggesting that this risk estimation tool underestimates cardiovascular risk in PLWH.
Identifiants
pubmed: 34650658
doi: 10.11604/pamj.2021.40.8.30855
pii: PAMJ-40-8
pmc: PMC8490168
doi:
Substances chimiques
Anti-HIV Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8Informations de copyright
Copyright: Liliane Mfeukeu Kuate et al.
Déclaration de conflit d'intérêts
The authors declared no competing interests.
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