Results of the Diaphragmatic Plication Database: 10 Years' Experience.


Journal

The Thoracic and cardiovascular surgeon
ISSN: 1439-1902
Titre abrégé: Thorac Cardiovasc Surg
Pays: Germany
ID NLM: 7903387

Informations de publication

Date de publication:
09 2023
Historique:
medline: 7 9 2023
pubmed: 17 10 2021
entrez: 16 10 2021
Statut: ppublish

Résumé

Unilateral diaphragmatic paralysis or paresis (UDP) in adults is an often overlooked disease which relevantly impairs the patient's lung function and quality of life. Particularly in idiopathic UDP, there is no evidence for conservative therapy and only little evidence for surgical therapy. The method involves retrospective single-center analysis of patients with UDP persistent for at least 1 year who were operated by diaphragmatic resection, plication, and augmentation with a polypropylene mesh. The patients were tested for lung and diaphragmatic function, six-minute walk test (6MWT), and blood gas analysis before, 3 and 12 months after surgery. In total, 85 patients received surgery for UDP. The most frequent reasons for UDP were idiopathic (67%), iatrogenic (mainly cardiac and cervical spine surgery; 24%), and trauma (9%). The mean operation time was 84 ± 24 minutes, the length of hospital stay 8.4 ± 3.9 days, chest tubes were removed after 11.7 ± 4.1 days. Overall morbidity was 42%, mortality 0%. Forced expiratory volume in one second (FEV Surgical therapy for UDP is highly effective in the long term. The superiority over conservative treatments needs to be evaluated prospectively with standardized physiotherapeutic protocols. FEV

Sections du résumé

BACKGROUND
Unilateral diaphragmatic paralysis or paresis (UDP) in adults is an often overlooked disease which relevantly impairs the patient's lung function and quality of life. Particularly in idiopathic UDP, there is no evidence for conservative therapy and only little evidence for surgical therapy.
METHODS
The method involves retrospective single-center analysis of patients with UDP persistent for at least 1 year who were operated by diaphragmatic resection, plication, and augmentation with a polypropylene mesh. The patients were tested for lung and diaphragmatic function, six-minute walk test (6MWT), and blood gas analysis before, 3 and 12 months after surgery.
RESULTS
In total, 85 patients received surgery for UDP. The most frequent reasons for UDP were idiopathic (67%), iatrogenic (mainly cardiac and cervical spine surgery; 24%), and trauma (9%). The mean operation time was 84 ± 24 minutes, the length of hospital stay 8.4 ± 3.9 days, chest tubes were removed after 11.7 ± 4.1 days. Overall morbidity was 42%, mortality 0%. Forced expiratory volume in one second (FEV
CONCLUSION
Surgical therapy for UDP is highly effective in the long term. The superiority over conservative treatments needs to be evaluated prospectively with standardized physiotherapeutic protocols. FEV

Identifiants

pubmed: 34655069
doi: 10.1055/s-0041-1735496
doi:

Substances chimiques

Uridine Diphosphate 58-98-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

483-489

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

None declared.

Auteurs

Nils Jurriaan Kosse (NJ)

Department of Thoracic Surgery, University Witten Herdecke Faculty of Health, Witten, Germany.
Lung Clinic Merheim/Thoracic Surgery, Kliniken der Stadt Köln gGmbH, Koln, Germany.

Thomas Galetin (T)

Department of Thoracic Surgery, University Witten Herdecke Faculty of Health, Witten, Germany.
Lung Clinic Merheim/Thoracic Surgery, Kliniken der Stadt Köln gGmbH, Koln, Germany.

Sarah Bettina Schwarz (SB)

Department of Pneumology, University Witten Herdecke Faculty of Health, Witten, Germany.
Lungclinic Merheim/Pneumology, Kliniken der Stadt Köln gGmbH, Koeln, Germany.

Tim Mathes (T)

Institut für Forschung in der operativen Medizin (IFOM), Universität Witten/Herdecke Fakultät für Gesundheit, Witten, Nordrhein-Westfalen, Germany.

Aris Koryllos (A)

Department of Thoracic Surgery, University Witten Herdecke Faculty of Health, Witten, Germany.
Lung Clinic Merheim/Thoracic Surgery, Kliniken der Stadt Köln gGmbH, Koln, Germany.

Alberto Lopez-Pastorini (A)

Department of Thoracic Surgery, University Witten Herdecke Faculty of Health, Witten, Germany.
Lung Clinic Merheim/Thoracic Surgery, Kliniken der Stadt Köln gGmbH, Koln, Germany.

Frank Beckers (F)

Department of Thoracic Surgery, St Vinzenz Hospital, Koeln, Germany.

Erich Stoelben (E)

Department of Thoracic Surgery, University Witten Herdecke Faculty of Health, Witten, Germany.
Lung Clinic Merheim/Thoracic Surgery, Kliniken der Stadt Köln gGmbH, Koln, Germany.

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