Studying mutation rate evolution in primates-the effects of computational pipelines and parameter choices.

computational pipeline de novo mutation false-negative rate false-positive rate germline mutation rate primates

Journal

GigaScience
ISSN: 2047-217X
Titre abrégé: Gigascience
Pays: United States
ID NLM: 101596872

Informations de publication

Date de publication:
21 10 2021
Historique:
received: 13 09 2021
accepted: 13 09 2021
entrez: 21 10 2021
pubmed: 22 10 2021
medline: 1 4 2022
Statut: ppublish

Résumé

This commentary investigates the important role of computational pipeline and parameter choices in performing mutation rate estimation, using the recent article published in this journal by Bergeron et al. entitled "The germline mutational process in rhesus macaque and its implications for phylogenetic dating" as an illustrative example.

Identifiants

pubmed: 34673929
pii: 6407243
doi: 10.1093/gigascience/giab069
pmc: PMC8529961
pii:
doi:

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press GigaScience.

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Auteurs

Susanne P Pfeifer (SP)

School of Life Sciences, Arizona State University, Tempe, AZ 85281, USA.
Center for Evolution and Medicine, Arizona State University, Tempe, AZ 85281, USA.
Center for Mechanisms of Evolution, Arizona State University, Tempe, AZ 85281, USA.

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Classifications MeSH