Family-based treatment for adolescent anorexia nervosa: Outcomes of a stepped-care model.

adolescence adolescent-centered care anorexia nervosa eating disorders family-based treatment family-centered care

Journal

The International journal of eating disorders
ISSN: 1098-108X
Titre abrégé: Int J Eat Disord
Pays: United States
ID NLM: 8111226

Informations de publication

Date de publication:
11 2021
Historique:
revised: 10 10 2021
received: 30 08 2021
accepted: 11 10 2021
pubmed: 23 10 2021
medline: 26 11 2021
entrez: 22 10 2021
Statut: ppublish

Résumé

Stepped-care models of treatment are underexplored in eating disorders. To enhance treatment outcomes, and informed by literature about adaptations to family-based treatment (FBT), we developed an FBT-based stepped-care model for adolescents with anorexia nervosa (AN) that was consistent with family preference (i.e., tailored) and responsive to adolescent needs (i.e., intensity). The aim of this study was to evaluate the effectiveness of this model in terms of remission at end-of-treatment. Adolescents (N = 82), aged 12-18 years (M = 15.1, SD = 1.8) and meeting Diagnostic and Statistical Manual of Mental Disorders 5th Edition criteria for AN, were assessed at baseline, Weeks 24 and 48. FBT was tailored to family preference and clinical need, with 16-18 sessions by Week 24. This was followed by three FBT booster sessions or an extension of FBT plus booster sessions (Week 48). The primary outcome was defined as weight > 95% of %median body mass index plus within 1 SD of the Eating Disorder Examination (EDE) global score community norms. Remission rates were 45.1% and 52.4% at Weeks 24 and 48, respectively. Commensurable improvements were evident across secondary outcomes (e.g., EDE subscale scores). As a reference point, remission rates compared positively with results from a recent randomized clinical trial from the same center and at the same time points (Week 24:45.1% vs. 32.1% and Week 48:52.4% vs. 30.2%). Controlling for propensity score, no statistically significant differences were observed. This stepped-care model, designed to be responsive to the individual needs of adolescents and their families, achieved encouraging rates of remission. This study provides an important signal that supports future clinical trials of stepped-care models for adolescents with AN.

Identifiants

pubmed: 34676907
doi: 10.1002/eat.23629
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1989-1997

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

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Auteurs

Daniel Le Grange (D)

Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, USA.
Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, Illinois, USA (Emeritus).

Martin Pradel (M)

Department of Pediatrics, The Royal Children's Hospital, Melbourne, Australia.

Danielle Pogos (D)

Department of Pediatrics, The Royal Children's Hospital, Melbourne, Australia.
Murdoch Children's Research Institute, Melbourne, Australia.

Michele Yeo (M)

Department of Pediatrics, The Royal Children's Hospital, Melbourne, Australia.

Elizabeth K Hughes (EK)

Murdoch Children's Research Institute, Melbourne, Australia.
Department of Pediatrics, The University of Melbourne, Melbourne, Australia.

Alicia Tompson (A)

Department of Pediatrics, The Royal Children's Hospital, Melbourne, Australia.

Andrew Court (A)

Department of Pediatrics, The Royal Children's Hospital, Melbourne, Australia.

Ross D Crosby (RD)

Sanford Center for Bio-Behavioral Research, Fargo, North Dakota, USA.
Department of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota, USA.

Susan M Sawyer (SM)

Department of Pediatrics, The Royal Children's Hospital, Melbourne, Australia.
Murdoch Children's Research Institute, Melbourne, Australia.
Department of Pediatrics, The University of Melbourne, Melbourne, Australia.

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