Thoracic Aortic Aneurysm: A Clinical Review.

Aortic Dissection Aortic Aneurysm, Thoracic / diagnosis Bicuspid Aortic Valve Disease Genetic Predisposition to Disease Humans Marfan Syndrome
Bicuspid aortic valve Loeys-Dietz syndrome Marfan syndrome Thoracic aortic aneurysm Thoracic aortic dissection Vascular Ehlers-Danlos syndrome

Journal

Cardiology clinics
ISSN: 1558-2264
Titre abrégé: Cardiol Clin
Pays: Netherlands
ID NLM: 8300331

Informations de publication

Date de publication:
Nov 2021
Historique:
entrez: 23 10 2021
pubmed: 24 10 2021
medline: 27 10 2021
Statut: ppublish

Résumé

Thoracic aortic aneurysms are common. Most thoracic aortic aneurysms are degenerative. However, some are associated with connective tissue disorders, bicuspid aortic valves, or familial/genetic predisposition. Most are asymptomatic, discovered incidentally on imaging. Aortic diameter is the best predictor of the natural history and risk of complications. Treating hypertension and smoking cessation can slow their growth. Surveillance imaging and referral for prophylactic aortic repair based on absolute aneurysm diameter is the primary means to decrease mortality from thoracic aortic aneurysm. We provide a practical evidence-based summary of the pathophysiology, risk factors, associated genetic syndromes, and clinical management of thoracic aortic aneurysms.

Identifiants

DOI: 10.1016/j.ccl.2021.06.003 PMID: 34686263
pubmed: 34686263
pii: S0733-8651(21)00053-9
doi: 10.1016/j.ccl.2021.06.003
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

505-515

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Ethan M Senser (EM)

Heart and Vascular Center, Dartmouth-Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA.

Shantum Misra (S)

Department of Medicine, Dartmouth-Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA.

Stanislav Henkin (S)

Heart and Vascular Center, Dartmouth-Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA. Electronic address: Stanislav.henkin@hitchcock.org.

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Classifications MeSH

questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Maladies de l'aorte › Syndrome aortique aigu › Dissection aortique › Thoracic Aortic Aneurysm: A Clinical Review.
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Maladies de l'aorte › Anévrysme de l'aorte › Anévrysme de l'aorte thoracique › Thoracic Aortic Aneurysm: A Clinical Review.
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Malformations › Malformations cardiovasculaires › Cardiopathies congénitales › Maladie de la valve aortique bicuspide › Thoracic Aortic Aneurysm: A Clinical Review.
questionsmedicales.fr › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › Thoracic Aortic Aneurysm: A Clinical Review.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Thoracic Aortic Aneurysm: A Clinical Review.
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies du tissu conjonctif › Syndrome de Marfan › Thoracic Aortic Aneurysm: A Clinical Review.