Dietary phytochemicals as modulators of human pregnane X receptor.
Agonists
antagonists
dietary phytochemicals
pregnane X receptor
Journal
Critical reviews in food science and nutrition
ISSN: 1549-7852
Titre abrégé: Crit Rev Food Sci Nutr
Pays: United States
ID NLM: 8914818
Informations de publication
Date de publication:
2023
2023
Historique:
medline:
3
7
2023
pubmed:
27
10
2021
entrez:
26
10
2021
Statut:
ppublish
Résumé
As a promiscuous xenobiotic sensor, pregnane X receptor (PXR) plays a crucial role in drug metabolism. Since dietary phytochemicals exhibit the potential to modulate human PXR, this review aims to summarize the plant-derived PXR modulators, including agonists, partial agonists, and antagonists. The crystal structures of the
Identifiants
pubmed: 34698593
doi: 10.1080/10408398.2021.1995322
doi:
Substances chimiques
Pregnane X Receptor
0
Receptors, Steroid
0
Resveratrol
Q369O8926L
Phytochemicals
0
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM