Physostigmine should be used more readily for antimuscarinic toxicity: PRO.


Journal

British journal of clinical pharmacology
ISSN: 1365-2125
Titre abrégé: Br J Clin Pharmacol
Pays: England
ID NLM: 7503323

Informations de publication

Date de publication:
01 2022
Historique:
revised: 06 08 2021
received: 09 07 2021
accepted: 10 08 2021
pubmed: 28 10 2021
medline: 12 4 2022
entrez: 27 10 2021
Statut: ppublish

Résumé

Physostigmine is the preferred treatment for antimuscarinic toxicity. Its use has a clear biological rationale and is supported by extensive clinical use which demonstrated effectiveness and safety.

Identifiants

pubmed: 34705298
doi: 10.1111/bcp.15120
doi:

Substances chimiques

Cholinesterase Inhibitors 0
Muscarinic Antagonists 0
Physostigmine 9U1VM840SP

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

58-60

Informations de copyright

© 2021 British Pharmacological Society.

Références

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Holzgrafe RE, Vondrell JJ, Mintz SM. Reversal of postoperative reactions to scopolamine with physostigmine. Anesth Anal. 1973;52(6):921-925.
Greene LT. Physostigmine treatment of anticholinergic-drug depression in postoperative patients. Anesth Anal. 1971;50(2):222-226.
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Auteurs

Andrew Dawson (A)

NSW Poisons Information Centre, Westmead Childrens Hospital, Sydney, Australia.
Central Clinical School, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia.

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Classifications MeSH