Fecal Microbiome Composition Does Not Predict Diet-Induced TMAO Production in Healthy Adults.

Adult Bacteria / metabolism Choline / metabolism Cross-Over Studies Diet Feces Gastrointestinal Microbiome Humans Lyases / metabolism Methylamines / blood Microbiota
fecal microbiome metagenomics trimethylamine N‐oxide trimethylamine lyase

Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
02 11 2021
Historique:
pubmed: 30 10 2021
medline: 1 3 2022
entrez: 29 10 2021
Statut: ppublish

Résumé

Background Trimethylamine-

Identifiants

DOI: 10.1161/JAHA.121.021934 PMID: 34713713 PMC: PMC8751816
pubmed: 34713713
doi: 10.1161/JAHA.121.021934
pmc: PMC8751816
doi:

Substances chimiques

Methylamines 0
Lyases EC 4.-
trimethyloxamine FLD0K1SJ1A
Choline N91BDP6H0X

Banques de données

ClinicalTrials.gov
['NCT01427855']

Types de publication

Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e021934

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL130819
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL144651
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK106000
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL103866
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL147883
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL126827
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007250
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL134622
Pays : United States

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Auteurs

Marc Ferrell (M)

Department of Cardiovascular and Metabolic Sciences Lerner Research Institute Cleveland Clinic Cleveland OH.
Department of Systems Biology and Bioinformatics Case Western Reserve University Cleveland OH.

Peter Bazeley (P)

Department of Quantitative Health Sciences Lerner Research Institute Cleveland Clinic Cleveland OH.

Zeneng Wang (Z)

Department of Cardiovascular and Metabolic Sciences Lerner Research Institute Cleveland Clinic Cleveland OH.
ORCID: 0000-0002-6455-8228

Bruce S Levison (BS)

Department of Cardiovascular and Metabolic Sciences Lerner Research Institute Cleveland Clinic Cleveland OH.

Xinmin S Li (XS)

Department of Cardiovascular and Metabolic Sciences Lerner Research Institute Cleveland Clinic Cleveland OH.

Xun Jia (X)

Department of Cardiovascular and Metabolic Sciences Lerner Research Institute Cleveland Clinic Cleveland OH.
ORCID: 0000-0002-1746-8879

Ronald M Krauss (RM)

University of California San Francisco Oakland CA.
ORCID: 0000-0002-1238-3489

Rob Knight (R)

Department of Pediatrics Department of Computer Science and Engineering Department of Bioengineering, and The Center for Microbiome Innovation University of California, San Diego La Jolla CA.
ORCID: 0000-0002-0975-9019

Aldons J Lusis (AJ)

Departments of Human Genetics and Medicine David Geffen School of Medicine University of California Los Angeles Los Angeles CA.
ORCID: 0000-0001-9013-0228

J C Garcia-Garcia (JC)

Life Sciences Transformative Platform Technologies Procter & Gamble Cincinnati OH.

Stanley L Hazen (SL)

Department of Cardiovascular and Metabolic Sciences Lerner Research Institute Cleveland Clinic Cleveland OH.
Department of Cardiovascular Medicine Heart, Vascular and Thoracic Institute, Cleveland Clinic Cleveland OH.
ORCID: 0000-0001-7124-6639

W H Wilson Tang (WHW)

Department of Cardiovascular and Metabolic Sciences Lerner Research Institute Cleveland Clinic Cleveland OH.
Department of Cardiovascular Medicine Heart, Vascular and Thoracic Institute, Cleveland Clinic Cleveland OH.
ORCID: 0000-0002-8335-735X

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