Myasthenia gravis after glioblastoma resection: paraneoplastic syndrome or coincidence? A unique case report and review of the literature.
Brain tumor
Glioblastoma
Myasthenia gravis
Neuromuscular junction
Paraneoplastic neurological syndrome
Journal
Acta neurochirurgica
ISSN: 0942-0940
Titre abrégé: Acta Neurochir (Wien)
Pays: Austria
ID NLM: 0151000
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
received:
18
06
2021
accepted:
14
10
2021
pubmed:
30
10
2021
medline:
8
3
2022
entrez:
29
10
2021
Statut:
ppublish
Résumé
Paraneoplastic neurological syndromes (PNS) can manifest with every type of malignancy. A well-known syndrome is myasthenia gravis (MG) in combination with thymomas. No association between primary brain tumors and neuromuscular disorders has been described. Here, we present a case of a 65-year-old patient who developed MG, following an uncomplicated, gross-total resection of a glioblastoma. To our knowledge, this is the first case describing the onset of MG during the early postoperative phase after glioblastoma resection. Current criteria of PNS are insufficient when the neurological syndrome is diagnosed at the time of a malignancy or shortly thereafter and should be revisited.
Identifiants
pubmed: 34714432
doi: 10.1007/s00701-021-05035-3
pii: 10.1007/s00701-021-05035-3
pmc: PMC8854242
doi:
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
423-427Informations de copyright
© 2021. The Author(s).
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