Methicillin-resistant Macrococcus canis in a human wound.
Antibiotic resistance
Dog
Human
Opportunistic pathogen
SCCmec element
WGS
Journal
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
ISSN: 1567-7257
Titre abrégé: Infect Genet Evol
Pays: Netherlands
ID NLM: 101084138
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
21
05
2021
revised:
01
09
2021
accepted:
22
10
2021
pubmed:
30
10
2021
medline:
15
1
2022
entrez:
29
10
2021
Statut:
ppublish
Résumé
A hemolytic Macrococcus canis strain (LI021) was isolated for the first time from a human skin infection. The complete genome of LI021 consisting of a 2,216,765-bp circular chromosome was obtained by de novo hybrid assembly of Illumina and Oxford Nanopore technology reads. Strain LI021 belonged to the new sequence type ST75 and was resistant to β-lactam antibiotics due to the presence of a methicillin resistance gene mecB. The mecB gene as well as putative hemolysin genes hlgB and hlgC were located on a novel composite pseudo (Ψ) SCCmec island. These findings show that a methicillin-resistant M. canis may be associated with human infection and indicate that this bacterium should be considered by human diagnostic laboratories.
Identifiants
pubmed: 34715385
pii: S1567-1348(21)00425-1
doi: 10.1016/j.meegid.2021.105125
pii:
doi:
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
105125Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.