Fibroblast growth factor 23 leads to endolysosomal routing of the renal phosphate cotransporters NaPi-IIa and NaPi-IIc in vivo.

Animals Endosomes / drug effects Fibroblast Growth Factor-23 / metabolism Fibroblast Growth Factors / metabolism Kidney / drug effects Kidney Tubules, Proximal / drug effects Lysosomes / drug effects Mice Parathyroid Hormone / metabolism Phosphates / metabolism Sodium-Phosphate Cotransporter Proteins, Type IIa / metabolism
calcitriol endocytosis fibroblast growth factor 23 phosphate proximal tubule

Journal

American journal of physiology. Renal physiology
ISSN: 1522-1466
Titre abrégé: Am J Physiol Renal Physiol
Pays: United States
ID NLM: 100901990

Informations de publication

Date de publication:
01 12 2021
Historique:
pubmed: 2 11 2021
medline: 22 12 2021
entrez: 1 11 2021
Statut: ppublish

Résumé

Na

Identifiants

DOI: 10.1152/ajprenal.00250.2021 PMID: 34719948
pubmed: 34719948
doi: 10.1152/ajprenal.00250.2021
doi:

Substances chimiques

Parathyroid Hormone 0
Phosphates 0
Sodium-Phosphate Cotransporter Proteins, Type IIa 0
Fibroblast Growth Factors 62031-54-3
Fibroblast Growth Factor-23 7Q7P4S7RRE

Banques de données

figshare
['10.6084/m9.figshare.16755073']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

F785-F798

Auteurs

Catharina J Küng (CJ)

Institute of Physiology, University of Zurich and National Center of Competence in Research Kidney.CH, Zurich, Switzerland.

Betül Haykir (B)

Institute of Physiology, University of Zurich and National Center of Competence in Research Kidney.CH, Zurich, Switzerland.

Udo Schnitzbauer (U)

Institute of Physiology, University of Zurich and National Center of Competence in Research Kidney.CH, Zurich, Switzerland.

Daniela Egli-Spichtig (D)

Institute of Physiology, University of Zurich and National Center of Competence in Research Kidney.CH, Zurich, Switzerland.

Nati Hernando (N)

Institute of Physiology, University of Zurich and National Center of Competence in Research Kidney.CH, Zurich, Switzerland.

Carsten A Wagner (CA)

Institute of Physiology, University of Zurich and National Center of Competence in Research Kidney.CH, Zurich, Switzerland.
ORCID: 0000-0002-9874-8898

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Endosomes › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Facteur-23 de croissance des fibroblastes › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Facteurs de croissance fibroblastique › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Néphrons › Tubules rénaux › Tubules contournés proximaux › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Lysosomes › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormone parathyroïdienne › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du phosphore › Acides du phosphore › Acides phosphoriques › Phosphates › Fibroblast growth factor 23 leads to...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Protéines transporteurs de solutés › Cotransporteurs sodium-phosphate de type II › Cotransporteurs sodium-phosphate de type IIa › Fibroblast growth factor 23 leads to...