Low-concentration povidone-iodine for the prevention of intraocular infections in ophthalmic surgery.
Journal
Current opinion in ophthalmology
ISSN: 1531-7021
Titre abrégé: Curr Opin Ophthalmol
Pays: United States
ID NLM: 9011108
Informations de publication
Date de publication:
01 Jan 2022
01 Jan 2022
Historique:
pubmed:
2
11
2021
medline:
15
12
2021
entrez:
1
11
2021
Statut:
ppublish
Résumé
Endophthamitis following intraocular surgery is rare using current antiseptic techniques, such as single application of 5% povidone-iodine to the ocular surface and adjuvant topical or intracameral antibiotics. Challenges remain, however, including increased multidrug-resistant bacterial endophthalmitis, increased fungal endophthalmitis, and the low but nonzero endophthalmitis rate attributable to the typical bacteria that colonize the ocular surface. Povidone-iodine has a wide spectrum of activity, including activity against novel pathogens, such as SARS-CoV-2. Povidone-iodine alternatives, such as hypochlorous acid can have significantly less efficacy in vitro against endophthalmitis isolates. Repetitive application of dilute povidone-iodine has an excellent safety profile and strong evidence base for efficacy. Povidone-iodine is widely available, inexpensive, and commonly used by ophthalmologists. The repetitive application of dilute povidone-iodine is a well studied, well tolerated, and efficacious way to transiently sterilize the ocular surface during intraocular surgery. Additional benefits include activity against multidrug-resistant bacteria, fungi, and lack of inducible resistance.
Identifiants
pubmed: 34720096
doi: 10.1097/ICU.0000000000000817
pii: 00055735-202201000-00007
doi:
Substances chimiques
Anti-Bacterial Agents
0
Anti-Infective Agents, Local
0
Povidone-Iodine
85H0HZU99M
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
28-34Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Références
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