The Metabolome of Carbapenem-Resistant Klebsiella pneumoniae Infection in Plasma.


Journal

Disease markers
ISSN: 1875-8630
Titre abrégé: Dis Markers
Pays: United States
ID NLM: 8604127

Informations de publication

Date de publication:
2021
Historique:
received: 17 08 2021
revised: 13 09 2021
accepted: 12 10 2021
entrez: 1 11 2021
pubmed: 2 11 2021
medline: 5 2 2022
Statut: epublish

Résumé

Carbapenem-resistant In this study, we comprehensively profile the metabolites of 20 CR-Kp-positive and 18 CR-Kp-negative patients in plasma by using 2D gas chromatography-time-of-flight mass spectrometry (GC×GC-TOFMS). We identified 58 metabolites that were carbapenem-resistant Our study provides valuable data to serve as potential targets for developing therapies against CR-Kp infection.

Identifiants

pubmed: 34721736
doi: 10.1155/2021/7155772
pmc: PMC8556109
doi:

Substances chimiques

Biomarkers 0
Carbapenems 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7155772

Informations de copyright

Copyright © 2021 Zhongwei Wen et al.

Déclaration de conflit d'intérêts

The authors report no conflict of interest.

Références

Arch Intern Med. 2002 May 13;162(9):1021-7
pubmed: 11996612
Biotechnol Adv. 2018 Jan - Feb;36(1):150-167
pubmed: 29056473
J Proteome Res. 2012 Mar 2;11(3):1844-54
pubmed: 22292465
Curr Opin Biotechnol. 2019 Feb;55:44-50
pubmed: 30138778
J Immunol. 2006 Sep 15;177(6):4002-11
pubmed: 16951363
Microb Drug Resist. 2018 May;24(4):447-454
pubmed: 28972857
FASEB J. 2018 Sep;32(9):4878-4888
pubmed: 29620942
J Assoc Physicians India. 2010 Dec;58 Suppl:41-4
pubmed: 21568008
Sci Rep. 2018 Jan 12;8(1):663
pubmed: 29330539
N Engl J Med. 2002 Feb 7;346(6):429-37
pubmed: 11832532
Mayo Clin Proc. 2010 Feb;85(2):139-44
pubmed: 20118389
Metabolites. 2019 Jun 27;9(7):
pubmed: 31252628
Metabolomics. 2018 Nov 17;14(11):152
pubmed: 30830421
Trends Biochem Sci. 2017 Apr;42(4):274-284
pubmed: 28196646
J Infect. 2011 Jan;62(1):26-33
pubmed: 21056057
FEMS Microbiol Rev. 2017 May 1;41(3):252-275
pubmed: 28521338
Microb Drug Resist. 2011 Jun;17(2):259-66
pubmed: 21352075
Front Cell Infect Microbiol. 2019 May 24;9:161
pubmed: 31179245
J Clin Microbiol. 2009 Apr;47(4):969-74
pubmed: 19213695
Diagn Microbiol Infect Dis. 2011 Apr;69(4):357-62
pubmed: 21396529
J Breath Res. 2016 May 10;10(2):027101
pubmed: 27163334

Auteurs

Zhongwei Wen (Z)

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.

Mei Liu (M)

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.

Dong Rui (D)

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.

Xiaoxiao Liao (X)

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.

Rui Su (R)

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.

Zhenming Tang (Z)

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.

Zhineng Wen (Z)

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.

Zhougui Ling (Z)

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH