Colistin resistance in
E. coli
MCR
colistin
lipopolysaccharide
polymyxin
resistance
Journal
Microbiology (Reading, England)
ISSN: 1465-2080
Titre abrégé: Microbiology (Reading)
Pays: England
ID NLM: 9430468
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
entrez:
1
11
2021
pubmed:
2
11
2021
medline:
14
1
2022
Statut:
ppublish
Résumé
Colistin is a polymyxin antibiotic of last resort for the treatment of infections caused by multi-drug-resistant Gram-negative bacteria. By targeting lipopolysaccharide (LPS), the antibiotic disrupts both the outer and cytoplasmic membranes, leading to bacterial death and lysis. Colistin resistance in
Identifiants
pubmed: 34723787
doi: 10.1099/mic.0.001104
pmc: PMC8743629
doi:
Substances chimiques
Anti-Bacterial Agents
0
Escherichia coli Proteins
0
MCR-1 protein, E coli
0
Polymyxins
0
Colistin
Z67X93HJG1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Medical Research Council
ID : MR/N014103/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_17162
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_15028
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 105603/Z/14/Z
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Department of Health
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M009505/1
Pays : United Kingdom
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