High-throughput imaging of ATG9A distribution as a diagnostic functional assay for adaptor protein complex 4-associated hereditary spastic paraplegia.

adaptor protein complex 4 biomarker functional assay hereditary spastic paraplegia high-throughput imaging

Journal

Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125

Informations de publication

Date de publication:
2021
Historique:
received: 07 04 2021
revised: 05 08 2021
accepted: 19 08 2021
entrez: 3 11 2021
pubmed: 4 11 2021
medline: 4 11 2021
Statut: epublish

Résumé

Adaptor protein complex 4-associated hereditary spastic paraplegia is caused by biallelic loss-of-function variants in

Identifiants

pubmed: 34729478
doi: 10.1093/braincomms/fcab221
pii: fcab221
pmc: PMC8557665
doi:

Types de publication

Journal Article

Langues

eng

Pagination

fcab221

Subventions

Organisme : NINDS NIH HHS
ID : K08 NS123552
Pays : United States
Organisme : NICHD NIH HHS
ID : P50 HD105351
Pays : United States
Organisme : NINDS NIH HHS
ID : R25 NS070682
Pays : United States

Informations de copyright

© The Author(s) (2021). Published by Oxford University Press on behalf of the Guarantors of Brain.

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Auteurs

Darius Ebrahimi-Fakhari (D)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA 02115, USA.

Julian E Alecu (JE)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Barbara Brechmann (B)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Division of Neuropediatrics and Inherited Metabolic Diseases, Center for Pediatrics and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.

Marvin Ziegler (M)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Ruprecht-Karls University Heidelberg, Medical School, 69120 Heidelberg, Germany.

Kathrin Eberhardt (K)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Hellen Jumo (H)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Angelica D'Amore (A)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Parham Habibzadeh (P)

Persian BayanGene Research and Training Center, Shiraz University of Medical Sciences, 71347 Shiraz, Iran.

Mohammad Ali Faghihi (MA)

Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL 33136, USA.

Jan L De Bleecker (JL)

Department of Neurology, Ghent University Hospital, 9000 Ghent, Belgium.

Sandrine Vuillaumier-Barrot (S)

Department of Biochemistry, AP-HP, Bichat Hospital, 75018 Paris, France.

Stéphane Auvin (S)

Pediatric Neurology Department, AP-HP, Robert Debré Hospital, 75019 Paris, France.

Filippo M Santorelli (FM)

Department of Molecular Medicine, IRCCS Fondazione Stella Maris, 56128 Pisa, Italy.

Sonja Neuser (S)

Institute of Human Genetics, University of Leipzig Medical Center, 04103 Leipzig, Germany.

Bernt Popp (B)

Institute of Human Genetics, University of Leipzig Medical Center, 04103 Leipzig, Germany.

Edward Yang (E)

Division of Neuroradiology, Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Lee Barrett (L)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA 02115, USA.

Alexandra K Davies (AK)

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

Afshin Saffari (A)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Division of Neuropediatrics and Inherited Metabolic Diseases, Center for Pediatrics and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.

Jennifer Hirst (J)

Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.

Mustafa Sahin (M)

Department of Neurology, The F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA 02115, USA.

Classifications MeSH