Extracellular Signal-Regulated Kinase1 (ERK1)-Mediated Phosphorylation of Voltage-Dependent Anion Channel (VDAC) Suppresses its Conductance.
Apoptosis
Bilayer electrophysiology
Extracellular signal-regulated kinase
Phosphorylation
Voltage-dependent anion channel
Journal
The Journal of membrane biology
ISSN: 1432-1424
Titre abrégé: J Membr Biol
Pays: United States
ID NLM: 0211301
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
received:
23
05
2021
accepted:
18
10
2021
pubmed:
4
11
2021
medline:
10
5
2022
entrez:
3
11
2021
Statut:
ppublish
Résumé
ERK1 is one of the members of the mitogen-activated protein kinases that regulate important cellular functions. VDAC is located at the outer membrane of mitochondria. Here, an interaction between VDAC and ERK1 has been studied on an artificial planar lipid bilayer using in vitro electrophysiology experiments. We report that VDAC is phosphorylated by ERK1 in the presence of Mg
Identifiants
pubmed: 34731249
doi: 10.1007/s00232-021-00205-x
pii: 10.1007/s00232-021-00205-x
doi:
Substances chimiques
Lipid Bilayers
0
Voltage-Dependent Anion Channels
0
Threonine
2ZD004190S
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
107-116Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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