Microvessels enhance vascularization and function of transplanted insulin-producing cells.


Journal

Cell metabolism
ISSN: 1932-7420
Titre abrégé: Cell Metab
Pays: United States
ID NLM: 101233170

Informations de publication

Date de publication:
02 11 2021
Historique:
entrez: 3 11 2021
pubmed: 4 11 2021
medline: 10 2 2022
Statut: ppublish

Résumé

Transplantation of insulin-producing cells is an emerging treatment for type 1 diabetes. A recent report in Cell Stem Cell (Aghazadeh et al., 2021) outlines a new approach that accelerates the engraftment and improves the survival and function of such cell transplants by mixing adipose tissue-derived ready-made microvessels with human pancreatic progenitor cells or cadaveric islets prior to transplantation.

Identifiants

pubmed: 34731653
pii: S1550-4131(21)00491-5
doi: 10.1016/j.cmet.2021.10.013
pii:
doi:

Substances chimiques

Insulins 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

2103-2105

Commentaires et corrections

Type : CommentOn

Informations de copyright

Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Alvin C Powers (AC)

Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; VA Tennessee Valley Healthcare System, Nashville, TN 37212, USA. Electronic address: al.powers@vumc.org.

Marcela Brissova (M)

Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA. Electronic address: marcela.brissova@vanderbilt.edu.

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Classifications MeSH