Marcela Brissova

Affiliations

Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN.
Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.

Publications (27)

Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally.

Diabetes

Avec: Holly A Cyphert , Emily M Walker , Yan Hang , Sangeeta Dhawan , Rachana Haliyur , Lauren Bonatakis , Dana Avrahami , Marcela Brissova , Klaus H Kaestner , Anil Bhushan , Alvin C Powers , Roland Stein

Combinatorial transcription factor profiles predict mature and functional human islet α and β cells.

JCI insight

Avec: Shristi Shrestha , Diane C Saunders , John T Walker , Joan Camunas-Soler , Xiao-Qing Dai , Rachana Haliyur , Radhika Aramandla , Greg Poffenberger , Nripesh Prasad , Rita Bottino , Roland Stein , Jean-Philippe Cartailler , Stephen Cj Parker , Patrick E MacDonald , Shawn E Levy , Alvin C Powers , Marcela Brissova

α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals.

The Journal of clinical investigation

Avec: Nicolai M Doliba , Andrea V Rozo , Jeffrey Roman , Wei Qin , Daniel Traum , Long Gao , Jinping Liu , Elisabetta Manduchi , Chengyang Liu , Maria L Golson , Golnaz Vahedi , Ali Naji , Franz M Matschinsky , Mark A Atkinson , Alvin C Powers , Marcela Brissova , Klaus H Kaestner , Doris A Stoffers , Auteur inconnu

Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.

Diabetes

Avec: Jordan J Wright , Adel Eskaros , Annika Windon , Rita Bottino , Regina Jenkins , Amber M Bradley , Radhika Aramandla , Sharon Philips , Hakmook Kang , Diane C Saunders , Marcela Brissova , Alvin C Powers

Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A.

Cell stem cell

Avec: Fabian L Cardenas-Diaz , Catherine Osorio-Quintero , Maria A Diaz-Miranda , Siddharth Kishore , Karla Leavens , Chintan Jobaliya , Diana Stanescu , Xilma Ortiz-Gonzalez , Christine Yoon , Christopher S Chen , Rachana Haliyur , Marcela Brissova , Alvin C Powers , Deborah L French , Paul Gadue

Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue.

Diabetologia

Avec: Boone M Prentice , Nathaniel J Hart , Neil Phillips , Rachana Haliyur , Audra Judd , Radhika Armandala , Jeffrey M Spraggins , Cindy L Lowe , Kelli L Boyd , Roland W Stein , Christopher V Wright , Jeremy L Norris , Alvin C Powers , Marcela Brissova , Richard M Caprioli

The Human Islet: Mini-Organ With Mega-Impact.

Endocrine reviews

Avec: John T Walker , Diane C Saunders , Marcela Brissova , Alvin C Powers

Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors.

Translational psychiatry

Avec: Despoina Aslanoglou , Suzanne Bertera , Marta Sánchez-Soto , R Benjamin Free , Jeongkyung Lee , Wei Zong , Xiangning Xue , Shristi Shrestha , Marcela Brissova , Ryan W Logan , Claes B Wollheim , Massimo Trucco , Vijay K Yechoor , David R Sibley , Rita Bottino , Zachary Freyberg

Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival.

Developmental cell

Avec: Ruiying Hu , Emily Walker , Chen Huang , Yanwen Xu , Chen Weng , Gillian E Erickson , Anastasia Coldren , Xiaodun Yang , Marcela Brissova , Irina Kaverina , Appakalai N Balamurugan , Christopher V E Wright , Yan Li , Roland Stein , Guoqiang Gu

Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis.

Cell metabolism

Avec: Diane C Saunders , Marcela Brissova , Neil Phillips , Shristi Shrestha , John T Walker , Radhika Aramandla , Greg Poffenberger , David K Flaherty , Kevin P Weller , Julie Pelletier , Tracy Cooper , Matt T Goff , John Virostko , Alena Shostak , E Danielle Dean , Dale L Greiner , Leonard D Shultz , Nripesh Prasad , Shawn E Levy , Robert H Carnahan , Chunhua Dai , Jean Sévigny , Alvin C Powers

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells.

bioRxiv : the preprint server for biology

Avec: Katie C Coate , Jeeyeon Cha , Shristi Shrestha , Wenliang Wang , Luciana Mateus Gonçalves , Joana Almaça , Meghan E Kapp , Maria Fasolino , Ashleigh Morgan , Chunhua Dai , Diane C Saunders , Rita Bottino , Radhika Aramandla , Regina Jenkins , Roland Stein , Klaus H Kaestner , Golnaz Vahedi , Hpap Consortium , Marcela Brissova , Alvin C Powers

Microvessels enhance vascularization and function of transplanted insulin-producing cells.

Cell metabolism

Avec: Alvin C Powers , Marcela Brissova

Genetic risk converges on regulatory networks mediating early type 2 diabetes.

Nature

Avec: John T Walker , Diane C Saunders , Vivek Rai , Hung-Hsin Chen , Peter Orchard , Chunhua Dai , Yasminye D Pettway , Alexander L Hopkirk , Conrad V Reihsmann , Yicheng Tao , Simin Fan , Shristi Shrestha , Arushi Varshney , Lauren E Petty , Jordan J Wright , Christa Ventresca , Samir Agarwala , Radhika Aramandla , Greg Poffenberger , Regina Jenkins , Shaojun Mei , Nathaniel J Hart , Sharon Phillips , Hakmook Kang , Dale L Greiner , Leonard D Shultz , Rita Bottino , Jie Liu , Jennifer E Below , Auteur inconnu , Stephen C J Parker , Alvin C Powers , Marcela Brissova

Integrated human pseudoislet system and microfluidic platform demonstrate differences in GPCR signaling in islet cells.

JCI insight

Avec: John T Walker , Rachana Haliyur , Heather A Nelson , Matthew Ishahak , Gregory Poffenberger , Radhika Aramandla , Conrad Reihsmann , Joseph R Luchsinger , Diane C Saunders , Peng Wang , Adolfo Garcia-Ocaña , Rita Bottino , Ashutosh Agarwal , Alvin C Powers , Marcela Brissova

Decreased pancreatic acinar cell number in type 1 diabetes.

Diabetologia

Avec: Jordan J Wright , Diane C Saunders , Chunhua Dai , Greg Poffenberger , Brynn Cairns , David V Serreze , David M Harlan , Rita Bottino , Marcela Brissova , Alvin C Powers

HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes.

Diabetes

Avec: Mark A Russell , Sambra D Redick , David M Blodgett , Sarah J Richardson , Pia Leete , Lars Krogvold , Knut Dahl-Jørgensen , Rita Bottino , Marcela Brissova , Jason M Spaeth , Jenny Aurielle B Babon , Rachana Haliyur , Alvin C Powers , Chaoxing Yang , Sally C Kent , Alan G Derr , Alper Kucukural , Manuel G Garber , Noel G Morgan , David M Harlan

Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.

The Journal of clinical investigation

Avec: Rachana Haliyur , Xin Tong , May Sanyoura , Shristi Shrestha , Jill Lindner , Diane C Saunders , Radhika Aramandla , Greg Poffenberger , Sambra D Redick , Rita Bottino , Nripesh Prasad , Shawn E Levy , Raymond D Blind , David M Harlan , Louis H Philipson , Roland W Stein , Marcela Brissova , Alvin C Powers

Pancreatlas: Applying an Adaptable Framework to Map the Human Pancreas in Health and Disease.

Patterns (New York, N.Y.)

Avec: Diane C Saunders , James Messmer , Irina Kusmartseva , Maria L Beery , Mingder Yang , Mark A Atkinson , Alvin C Powers , Jean-Philippe Cartailler , Marcela Brissova

Human Pseudoislet System for Synchronous Assessment of Fluorescent Biosensor Dynamics and Hormone Secretory Profiles.

Journal of visualized experiments : JoVE

Avec: Tiffany M Richardson , Yasminye D Pettway , John T Walker , Heather A Nelson , Matthew Ishahak , Gregory Poffenberger , Radhika Aramandla , Conrad Reihsmann , Ashutosh Agarwal , Alvin C Powers , Marcela Brissova

AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics.

Nature communications

Avec: Aanchal Mongia , Fatema Tuz Zohora , Noah G Burget , Yeqiao Zhou , Diane C Saunders , Yue J Wang , Marcela Brissova , Alvin C Powers , Klaus H Kaestner , Golnaz Vahedi , Ali Naji , Gregory W Schwartz , Robert B Faryabi

Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes.

Journal of the Endocrine Society

Avec: Rachana Haliyur , John T Walker , May Sanyoura , Conrad V Reihsmann , Shristi Shrestha , Radhika Aramandla , Greg Poffenberger , Andrea H Ramirez , Sambra D Redick , Jenny Aurielle B Babon , Nripesh Prasad , Robert A Hegele , Sally C Kent , David M Harlan , Rita Bottino , Louis H Philipson , Marcela Brissova , Alvin C Powers

Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration.

NPJ Regenerative medicine

Avec: Diane C Saunders , Kristie I Aamodt , Tiffany M Richardson , Alexander J Hopkirk , Radhika Aramandla , Greg Poffenberger , Regina Jenkins , David K Flaherty , Nripesh Prasad , Shawn E Levy , Alvin C Powers , Marcela Brissova

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells.

Cell metabolism

The human α cell in health and disease.

The Journal of endocrinology

Avec: Yasminye D Pettway , Diane C Saunders , Marcela Brissova

AnnoSpat annotates cell types and quantifies cellular arrangements from spatial proteomics.

bioRxiv : the preprint server for biology

Avec: Aanchal Mongia , Diane C Saunders , Yue J Wang , Marcela Brissova , Alvin C Powers , Klaus H Kaestner , Golnaz Vahedi , Ali Naji , Gregory W Schwartz , Robert B Faryabi

Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss.

American journal of physiology. Endocrinology and metabolism

Avec: Tiffany M Richardson , Diane C Saunders , Rachana Haliyur , Shristi Shrestha , Jean-Philippe Cartailler , Rachel B Reinert , Jenna Petronglo , Rita Bottino , Radhika Aramandla , Amber M Bradley , Regina Jenkins , Sharon Phillips , Hakmook Kang , Auteur inconnu , Alejandro Caicedo , Alvin C Powers , Marcela Brissova

CNTools: A computational toolbox for cellular neighborhood analysis from multiplexed images.

PLoS computational biology

Avec: Yicheng Tao , Fan Feng , Xin Luo , Conrad V Reihsmann , Alexander L Hopkirk , Jean-Philippe Cartailler , Marcela Brissova , Stephen C J Parker , Diane C Saunders , Jie Liu

Réseau de co-auteurs

Alvin C Powers 23 collaborations

Diane C Saunders 17 collaborations

Radhika Aramandla 12 collaborations

Rita Bottino 12 collaborations

Rachana Haliyur 9 collaborations

Shristi Shrestha 9 collaborations

John T Walker 7 collaborations

Greg Poffenberger 7 collaborations

Klaus H Kaestner 6 collaborations

Regina Jenkins 6 collaborations

Roland Stein 5 collaborations

Nripesh Prasad 5 collaborations

Golnaz Vahedi 5 collaborations

Chunhua Dai 5 collaborations

Jean-Philippe Cartailler 4 collaborations

Shawn E Levy 4 collaborations

None None 4 collaborations

David M Harlan 4 collaborations

Ali Naji 3 collaborations

Jordan J Wright 3 collaborations

Hakmook Kang 3 collaborations

Yasminye D Pettway 3 collaborations

Conrad V Reihsmann 3 collaborations

Sambra D Redick 3 collaborations

Tiffany M Richardson 3 collaborations

Mark A Atkinson 2 collaborations

Amber M Bradley 2 collaborations

Nathaniel J Hart 2 collaborations

Neil Phillips 2 collaborations

Roland W Stein 2 collaborations

David K Flaherty 2 collaborations

Dale L Greiner 2 collaborations

Leonard D Shultz 2 collaborations

Katie C Coate 2 collaborations

Jeeyeon Cha 2 collaborations

Wenliang Wang 2 collaborations

Luciana Mateus Gonçalves 2 collaborations

Joana Almaça 2 collaborations

Meghan E Kapp 2 collaborations

Maria Fasolino 2 collaborations

Ashleigh Morgan 2 collaborations

Alexander L Hopkirk 2 collaborations

Yicheng Tao 2 collaborations

Sharon Phillips 2 collaborations

Jie Liu 2 collaborations

Stephen C J Parker 2 collaborations

Heather A Nelson 2 collaborations

Matthew Ishahak 2 collaborations

Gregory Poffenberger 2 collaborations

Conrad Reihsmann 2 collaborations

Ashutosh Agarwal 2 collaborations

Jenny Aurielle B Babon 2 collaborations

Sally C Kent 2 collaborations

May Sanyoura 2 collaborations

Louis H Philipson 2 collaborations

Aanchal Mongia 2 collaborations

Yue J Wang 2 collaborations

Gregory W Schwartz 2 collaborations

Robert B Faryabi 2 collaborations

Holly A Cyphert 1 collaboration

Emily M Walker 1 collaboration

Yan Hang 1 collaboration

Sangeeta Dhawan 1 collaboration

Lauren Bonatakis 1 collaboration

Dana Avrahami 1 collaboration

Anil Bhushan 1 collaboration

Joan Camunas-Soler 1 collaboration

Xiao-Qing Dai 1 collaboration

Stephen Cj Parker 1 collaboration

Patrick E MacDonald 1 collaboration

Nicolai M Doliba 1 collaboration

Andrea V Rozo 1 collaboration

Jeffrey Roman 1 collaboration

Wei Qin 1 collaboration

Daniel Traum 1 collaboration

Long Gao 1 collaboration

Jinping Liu 1 collaboration

Elisabetta Manduchi 1 collaboration

Chengyang Liu 1 collaboration

Maria L Golson 1 collaboration

Franz M Matschinsky 1 collaboration

Doris A Stoffers 1 collaboration

Adel Eskaros 1 collaboration

Annika Windon 1 collaboration

Sharon Philips 1 collaboration

Fabian L Cardenas-Diaz 1 collaboration

Catherine Osorio-Quintero 1 collaboration

Maria A Diaz-Miranda 1 collaboration

Siddharth Kishore 1 collaboration

Karla Leavens 1 collaboration

Chintan Jobaliya 1 collaboration

Diana Stanescu 1 collaboration

Xilma Ortiz-Gonzalez 1 collaboration

Christine Yoon 1 collaboration

Christopher S Chen 1 collaboration

Deborah L French 1 collaboration

Paul Gadue 1 collaboration

Boone M Prentice 1 collaboration

Audra Judd 1 collaboration

Radhika Armandala 1 collaboration

Jeffrey M Spraggins 1 collaboration

Cindy L Lowe 1 collaboration

Kelli L Boyd 1 collaboration

Christopher V Wright 1 collaboration

Jeremy L Norris 1 collaboration

Richard M Caprioli 1 collaboration

Despoina Aslanoglou 1 collaboration

Suzanne Bertera 1 collaboration

Marta Sánchez-Soto 1 collaboration

R Benjamin Free 1 collaboration

Jeongkyung Lee 1 collaboration

Wei Zong 1 collaboration

Xiangning Xue 1 collaboration

Ryan W Logan 1 collaboration

Claes B Wollheim 1 collaboration

Massimo Trucco 1 collaboration

Vijay K Yechoor 1 collaboration

David R Sibley 1 collaboration

Zachary Freyberg 1 collaboration

Ruiying Hu 1 collaboration

Emily Walker 1 collaboration

Chen Huang 1 collaboration

Yanwen Xu 1 collaboration

Chen Weng 1 collaboration

Gillian E Erickson 1 collaboration

Anastasia Coldren 1 collaboration

Xiaodun Yang 1 collaboration

Irina Kaverina 1 collaboration

Appakalai N Balamurugan 1 collaboration

Christopher V E Wright 1 collaboration

Yan Li 1 collaboration

Guoqiang Gu 1 collaboration

Kevin P Weller 1 collaboration

Julie Pelletier 1 collaboration

Tracy Cooper 1 collaboration

Matt T Goff 1 collaboration

John Virostko 1 collaboration

Alena Shostak 1 collaboration

E Danielle Dean 1 collaboration

Robert H Carnahan 1 collaboration

Jean Sévigny 1 collaboration

Hpap Consortium 1 collaboration

Vivek Rai 1 collaboration

Hung-Hsin Chen 1 collaboration

Peter Orchard 1 collaboration

Simin Fan 1 collaboration

Arushi Varshney 1 collaboration

Lauren E Petty 1 collaboration

Christa Ventresca 1 collaboration

Samir Agarwala 1 collaboration

Shaojun Mei 1 collaboration

Jennifer E Below 1 collaboration

Joseph R Luchsinger 1 collaboration

Peng Wang 1 collaboration

Adolfo Garcia-Ocaña 1 collaboration

Brynn Cairns 1 collaboration

David V Serreze 1 collaboration

Mark A Russell 1 collaboration

David M Blodgett 1 collaboration

Sarah J Richardson 1 collaboration

Pia Leete 1 collaboration

Lars Krogvold 1 collaboration

Knut Dahl-Jørgensen 1 collaboration

Jason M Spaeth 1 collaboration

Chaoxing Yang 1 collaboration

Alan G Derr 1 collaboration

Alper Kucukural 1 collaboration

Manuel G Garber 1 collaboration

Noel G Morgan 1 collaboration

Xin Tong 1 collaboration

Jill Lindner 1 collaboration

Raymond D Blind 1 collaboration

James Messmer 1 collaboration

Irina Kusmartseva 1 collaboration

Maria L Beery 1 collaboration

Mingder Yang 1 collaboration

Fatema Tuz Zohora 1 collaboration

Noah G Burget 1 collaboration

Yeqiao Zhou 1 collaboration

Andrea H Ramirez 1 collaboration

Robert A Hegele 1 collaboration

Kristie I Aamodt 1 collaboration

Alexander J Hopkirk 1 collaboration

Rachel B Reinert 1 collaboration

Jenna Petronglo 1 collaboration

Alejandro Caicedo 1 collaboration

Fan Feng 1 collaboration

Xin Luo 1 collaboration