Antibacterial and antiplaque efficacy of a lactoperoxidase-thiocyanate-hydrogen-peroxide-system-containing lozenge.
Antiseptic
Dental plaque
Essential oil
Lactoperoxidase-thiocyanate-hydrogen peroxide-system-containing lozenge
Mouth hygiene product
Journal
BMC microbiology
ISSN: 1471-2180
Titre abrégé: BMC Microbiol
Pays: England
ID NLM: 100966981
Informations de publication
Date de publication:
03 11 2021
03 11 2021
Historique:
received:
16
04
2021
accepted:
21
09
2021
entrez:
4
11
2021
pubmed:
5
11
2021
medline:
22
1
2022
Statut:
epublish
Résumé
Antimicrobial agents are considered valuable adjuncts to mechanical methods of plaque control. However, their long-term use can be limited because of side effects. Therefore, using physiological substances is promising due to no risk of development, for example, of microbial resistances, allergies or DNA damaging. The lactoperoxidase-thiocyanate-hydrogen peroxide system (LPO-system) is a highly effective antimicrobial system. This study aimed to evaluate in a randomized study with a four-replicate cross-over design the effectiveness of two oral hygiene lozenges containing LPO-system in oral hygiene. After using the mouth rinse as positive control (A) and allocated test lozenges (B) (0.083% H The results indicate that lozenges containing a complete LPO-system, inhibiting plaque regrowth and reducing cariogenic bacteria, may be used in the daily oral hygiene.
Sections du résumé
BACKGROUND
Antimicrobial agents are considered valuable adjuncts to mechanical methods of plaque control. However, their long-term use can be limited because of side effects. Therefore, using physiological substances is promising due to no risk of development, for example, of microbial resistances, allergies or DNA damaging. The lactoperoxidase-thiocyanate-hydrogen peroxide system (LPO-system) is a highly effective antimicrobial system. This study aimed to evaluate in a randomized study with a four-replicate cross-over design the effectiveness of two oral hygiene lozenges containing LPO-system in oral hygiene.
RESULTS
After using the mouth rinse as positive control (A) and allocated test lozenges (B) (0.083% H
CONCLUSIONS
The results indicate that lozenges containing a complete LPO-system, inhibiting plaque regrowth and reducing cariogenic bacteria, may be used in the daily oral hygiene.
Identifiants
pubmed: 34732139
doi: 10.1186/s12866-021-02333-9
pii: 10.1186/s12866-021-02333-9
pmc: PMC8564979
doi:
Substances chimiques
Anti-Bacterial Agents
0
Mouthwashes
0
Hydrogen Peroxide
BBX060AN9V
Lactoperoxidase
EC 1.11.1.-
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
302Informations de copyright
© 2021. The Author(s).
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