Fasting does not guarantee empty stomach in the intensive care unit: A prospective ultrasonographic evaluation (The NUTRIGUS study).

Airway management Critical care Empty stomach Fasting Gastric antral area Gastric ultrasound Point-of-care-ultrasound

Journal

Anaesthesia, critical care & pain medicine
ISSN: 2352-5568
Titre abrégé: Anaesth Crit Care Pain Med
Pays: France
ID NLM: 101652401

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 30 07 2021
revised: 15 09 2021
accepted: 16 09 2021
pubmed: 8 11 2021
medline: 25 12 2021
entrez: 7 11 2021
Statut: ppublish

Résumé

In the intensive care unit (ICU), a fasting period is usually respected to avoid gastric aspiration during airway management procedures. Since there are no recognised guidelines, intensive care physicians balance the aspiration risk with the negative consequences of underfeeding. Our objective was to determine the impact of fasting on gastric emptying in critically ill patients by using gastric ultrasound. Among the 112 patients that met the inclusion criteria, 100 patients were analysed. Gastric ultrasonography was performed immediately before extubation. Patients with either 1/ an absence of visualised gastric content (qualitative evaluation) or 2/ a gastric volume < 1.5 mll/kg in case of clear fluid gastric content (quantitative evaluation) were classified as having an empty stomach. In our study, twenty-six (26%) patients had a full stomach at the time of extubation. The incidence of full stomach was not significantly different between patients who fasted < 6 h or patients who fasted ≥ 6 h. Among the 57 patients receiving enteral nutrition (EN) within the last 48 h, there was no correlation between the duration of EN interruption and the GAA. The absence of EN was not associated with an empty stomach. At the time of extubation, the incidence of full stomach was high and not associated with the fasting characteristics (duration/absence of EN). Our results support the notions that fasting before airway management procedures is not a universal paradigm and that gastric ultrasound might represent a useful tool in the tailoring process. CLINICALTRIALS.GOV: NCT04245878.

Sections du résumé

BACKGROUND BACKGROUND
In the intensive care unit (ICU), a fasting period is usually respected to avoid gastric aspiration during airway management procedures. Since there are no recognised guidelines, intensive care physicians balance the aspiration risk with the negative consequences of underfeeding. Our objective was to determine the impact of fasting on gastric emptying in critically ill patients by using gastric ultrasound.
MATERIAL AND METHODS METHODS
Among the 112 patients that met the inclusion criteria, 100 patients were analysed. Gastric ultrasonography was performed immediately before extubation. Patients with either 1/ an absence of visualised gastric content (qualitative evaluation) or 2/ a gastric volume < 1.5 mll/kg in case of clear fluid gastric content (quantitative evaluation) were classified as having an empty stomach.
MAIN FINDINGS RESULTS
In our study, twenty-six (26%) patients had a full stomach at the time of extubation. The incidence of full stomach was not significantly different between patients who fasted < 6 h or patients who fasted ≥ 6 h. Among the 57 patients receiving enteral nutrition (EN) within the last 48 h, there was no correlation between the duration of EN interruption and the GAA. The absence of EN was not associated with an empty stomach.
CONCLUSION CONCLUSIONS
At the time of extubation, the incidence of full stomach was high and not associated with the fasting characteristics (duration/absence of EN). Our results support the notions that fasting before airway management procedures is not a universal paradigm and that gastric ultrasound might represent a useful tool in the tailoring process. CLINICALTRIALS.GOV: NCT04245878.

Identifiants

pubmed: 34743035
pii: S2352-5568(21)00179-X
doi: 10.1016/j.accpm.2021.100975
pii:
doi:

Banques de données

ClinicalTrials.gov
['NCT04245878']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

100975

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

Auteurs

Maxime Nguyen (M)

Department of Anaesthesiology and Intensive Care, Dijon University Hospital, F-21000 Dijon, France; University of Burgundy and Franche-Comté, LNC UMR1231, F-21000 Dijon, France; INSERM, LNC UMR1231, F-21000 Dijon, France; FCS Bourgogne-Franche Comté, LipSTIC LabEx, F-21000 Dijon, France. Electronic address: maxime.nguyen-soenen@chu-dijon.fr.

Anne Drihem (A)

Department of Anaesthesiology and Intensive Care, Dijon University Hospital, F-21000 Dijon, France.

Viven Berthoud (V)

Department of Anaesthesiology and Intensive Care, Dijon University Hospital, F-21000 Dijon, France.

Ophélie Dransart-Raye (O)

Department of Anaesthesiology and Intensive Care, Dijon University Hospital, F-21000 Dijon, France.

Loic Bartamian (L)

Department of Anaesthesiology and Intensive Care, Dijon University Hospital, F-21000 Dijon, France.

Isabelle Gounot (I)

Department of Anaesthesiology and Intensive Care, Dijon University Hospital, F-21000 Dijon, France.

Pierre-Grégoire Guinot (PG)

Department of Anaesthesiology and Intensive Care, Dijon University Hospital, F-21000 Dijon, France; University of Burgundy and Franche-Comté, LNC UMR1231, F-21000 Dijon, France; INSERM, LNC UMR1231, F-21000 Dijon, France; FCS Bourgogne-Franche Comté, LipSTIC LabEx, F-21000 Dijon, France.

Belaid Bouhemad (B)

Department of Anaesthesiology and Intensive Care, Dijon University Hospital, F-21000 Dijon, France; University of Burgundy and Franche-Comté, LNC UMR1231, F-21000 Dijon, France; INSERM, LNC UMR1231, F-21000 Dijon, France; FCS Bourgogne-Franche Comté, LipSTIC LabEx, F-21000 Dijon, France.

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