Effects of different types of allogeneic hematopoietic stem cell transplantation donors on Philadelphia chromosome-positive acute lymphoblastic leukemia during the tyrosine kinase inhibitor era: A systematic review and meta-analysis.


Journal

Hematology/oncology and stem cell therapy
ISSN: 2589-0646
Titre abrégé: Hematol Oncol Stem Cell Ther
Pays: Saudi Arabia
ID NLM: 101468532

Informations de publication

Date de publication:
04 Apr 2023
Historique:
received: 14 06 2021
accepted: 23 09 2021
medline: 10 4 2023
pubmed: 9 11 2021
entrez: 8 11 2021
Statut: epublish

Résumé

Matched donor (MD) allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently the preferred choice of treatment for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph Studies in EMBASE and MEDLINE between inception and December 2020 were identified using search terms related to "Ph Fourteen cohort studies were identified for the meta-analysis. Haploidentical (HID)-HSCT for Ph This systematic review and meta-analysis showed that HID-HSCT is as effective as MD-HSCT in Ph

Sections du résumé

BACKGROUND BACKGROUND
Matched donor (MD) allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently the preferred choice of treatment for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph
METHODS METHODS
Studies in EMBASE and MEDLINE between inception and December 2020 were identified using search terms related to "Ph
RESULTS RESULTS
Fourteen cohort studies were identified for the meta-analysis. Haploidentical (HID)-HSCT for Ph
CONCLUSION CONCLUSIONS
This systematic review and meta-analysis showed that HID-HSCT is as effective as MD-HSCT in Ph

Identifiants

pubmed: 34743893
pii: S1658-3876(21)00091-1
doi: 10.1016/j.hemonc.2021.09.007
doi:

Substances chimiques

Tyrosine Kinase Inhibitors 0
Protein Kinase Inhibitors 0

Types de publication

Meta-Analysis Systematic Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

197-208

Auteurs

Ben Ponvilawan (B)

Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Weerapat Owattanapanich (W)

Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Nipith Charoenngam (N)

Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Smith Kungwankiattichai (S)

Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

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Classifications MeSH