N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y

Amino Acid Sequence Arginine / chemistry Cyclization HEK293 Cells Humans Ligands Molecular Docking Simulation Neuropeptide Y / metabolism Protein Binding Receptors, Neuropeptide Y / chemistry

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
25 11 2021
Historique:
pubmed: 9 11 2021
medline: 29 1 2022
entrez: 8 11 2021
Statut: ppublish

Résumé

The family of neuropeptide Y (NPY) receptors comprises four subtypes (Y

Identifiants

DOI: 10.1021/acs.jmedchem.1c01574 PMID: 34748345
pubmed: 34748345
doi: 10.1021/acs.jmedchem.1c01574
doi:

Substances chimiques

Ligands 0
Neuropeptide Y 0
Receptors, Neuropeptide Y 0
neuropeptide Y4 receptor 55F8T1GN3X
Arginine 94ZLA3W45F

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

16746-16769

Auteurs

Adam Konieczny (A)

Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany.

Marcus Conrad (M)

Institute of Biochemistry, Emil-Fischer-Center, Friedrich-Alexander-University Erlangen-Nürnberg, Fahrstraße 17, D-91054 Erlangen, Germany.
ORCID: 0000-0002-6352-9046

Fabian J Ertl (FJ)

Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany.
ORCID: 0000-0001-7195-4387

Jakob Gleixner (J)

Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany.

Albert O Gattor (AO)

Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany.
ORCID: 0000-0001-5166-2168

Lukas Grätz (L)

Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany.
ORCID: 0000-0001-6755-0742

Maximilian F Schmidt (MF)

Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-University Erlangen-Nürnberg, Nikolaus-Fiebiger-Straße 10, D-91058 Erlangen, Germany.
ORCID: 0000-0002-7055-2439

Eduard Neu (E)

Department of Chemistry and Pharmacy, Computer-Chemistry-Center, Friedrich-Alexander-University Erlangen-Nürnberg, Nägelsbachstraße 25, D-91052 Erlangen, Germany.
ORCID: 0000-0003-2999-1488

Anselm H C Horn (AHC)

Institute of Biochemistry, Emil-Fischer-Center, Friedrich-Alexander-University Erlangen-Nürnberg, Fahrstraße 17, D-91054 Erlangen, Germany.
ORCID: 0000-0003-3539-8103

David Wifling (D)

Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany.

Peter Gmeiner (P)

Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-University Erlangen-Nürnberg, Nikolaus-Fiebiger-Straße 10, D-91058 Erlangen, Germany.
ORCID: 0000-0002-4127-197X

Timothy Clark (T)

Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-University Erlangen-Nürnberg, Nikolaus-Fiebiger-Straße 10, D-91058 Erlangen, Germany.
Department of Chemistry and Pharmacy, Computer-Chemistry-Center, Friedrich-Alexander-University Erlangen-Nürnberg, Nägelsbachstraße 25, D-91052 Erlangen, Germany.
ORCID: 0000-0001-7931-4659

Heinrich Sticht (H)

Institute of Biochemistry, Emil-Fischer-Center, Friedrich-Alexander-University Erlangen-Nürnberg, Fahrstraße 17, D-91054 Erlangen, Germany.
ORCID: 0000-0001-5644-045X

Max Keller (M)

Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany.
ORCID: 0000-0002-8095-8627

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Arginine › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Métabolisme › Cyclisation › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Neuropeptides › Neuropeptide Y › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › N-Terminus to Arginine Side-Chain Cyclization...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur aux neuropeptides › Récepteur neuropeptide Y › N-Terminus to Arginine Side-Chain Cyclization...