Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
RNAP-σ70
RamA
antibiotic resistance
class I and class II activators
cryoEM structures
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
ISSN: 2198-3844
Titre abrégé: Adv Sci (Weinh)
Pays: Germany
ID NLM: 101664569
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
revised:
09
10
2021
received:
23
08
2021
pubmed:
12
11
2021
medline:
22
3
2022
entrez:
11
11
2021
Statut:
ppublish
Résumé
Transcription activator RamA is linked to multidrug resistance of Klebsiella pneumoniae through controlling genes that encode efflux pumps (acrA) and porin-regulating antisense RNA (micF). In bacteria, σ
Identifiants
pubmed: 34761556
doi: 10.1002/advs.202103669
pmc: PMC8811837
doi:
Substances chimiques
Anti-Bacterial Agents
0
Bacterial Proteins
0
RamA protein, Klebsiella
0
Trans-Activators
0
Transcription Factors
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2103669Subventions
Organisme : National Natural Science Foundation of China
ID : 81773785
Organisme : China International Medical Foundation
ID : Z-2018-35-2003
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/N007816/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S014934/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P007503/1
Pays : United Kingdom
Organisme : National Natural Science Foundation of China
ID : 81401699
Organisme : Medical Research Council
ID : MR/N006828/1
Pays : United Kingdom
Organisme : National Natural Science Foundation of China
ID : 81991531
Informations de copyright
© 2021 The Authors. Advanced Science published by Wiley-VCH GmbH.
Références
PLoS One. 2011;6(7):e22161
pubmed: 21811569
Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19830-5
pubmed: 19903881
J Mol Biol. 1984 Dec 25;180(4):881-909
pubmed: 6098691
J Bacteriol. 1995 Dec;177(24):7100-4
pubmed: 8522515
Mol Microbiol. 1999 Nov;34(3):431-41
pubmed: 10564485
Curr Opin Microbiol. 2001 Apr;4(2):132-7
pubmed: 11282467
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
Antimicrob Agents Chemother. 2008 Sep;52(9):3430-2
pubmed: 18625776
Cell. 1999 Sep 17;98(6):811-24
pubmed: 10499798
Science. 2017 Nov 17;358(6365):947-951
pubmed: 29146813
Science. 2015 Aug 21;349(6250):882-5
pubmed: 26293966
Int J Antimicrob Agents. 2011 Jul;38(1):39-45
pubmed: 21514798
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):355-67
pubmed: 21460454
J Mol Biol. 1989 Mar 5;206(1):41-57
pubmed: 2649687
Adv Sci (Weinh). 2022 Feb;9(4):e2103669
pubmed: 34761556
Nat Methods. 2017 Mar;14(3):290-296
pubmed: 28165473
Antimicrob Agents Chemother. 2010 Jun;54(6):2720-3
pubmed: 20350947
Int J Antimicrob Agents. 2019 Aug;54(2):223-227
pubmed: 31200021
PLoS Biol. 2020 Apr 20;18(4):e3000706
pubmed: 32310937
Anal Biochem. 2016 Jun 15;503:56-7
pubmed: 27036618
J Mol Biol. 2019 Sep 20;431(20):4067-4077
pubmed: 30998934
Int J Antimicrob Agents. 2021 Feb;57(2):106251
pubmed: 33259915
Acta Crystallogr D Biol Crystallogr. 2012 Apr;68(Pt 4):352-67
pubmed: 22505256
J Antimicrob Chemother. 2016 Jul;71(7):1820-5
pubmed: 27029850
Elife. 2018 Nov 09;7:
pubmed: 30412051
Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10413-8
pubmed: 9724717
Cell. 1990 Aug 24;62(4):733-43
pubmed: 2167178
Mol Microbiol. 2002 Jan;43(2):355-70
pubmed: 11985714
Curr Opin Struct Biol. 2004 Feb;14(1):10-20
pubmed: 15102444
Nat Rev Microbiol. 2016 Oct;14(10):638-50
pubmed: 27498839
Science. 2016 Jun 10;352(6291):1330-3
pubmed: 27284196
Nat Methods. 2017 Apr;14(4):331-332
pubmed: 28250466
Microbiology (Reading). 1995 Aug;141 ( Pt 8):1909-1920
pubmed: 7551053
J Struct Biol. 2007 Jan;157(1):281-7
pubmed: 16963278
Cell. 1994 Dec 2;79(5):743-6
pubmed: 8001112
Microb Drug Resist. 2018 Nov;24(9):1277-1283
pubmed: 29653477