Peripherally administered cannabinoid receptor 2 (CB
Animals
Cannabinoid Receptor Agonists
/ pharmacology
Chemokine CCL2
/ metabolism
Chromones
/ pharmacology
Ganglia, Spinal
/ drug effects
Glial Fibrillary Acidic Protein
/ metabolism
Hyperalgesia
/ drug therapy
Mice
Mice, Knockout
Receptor, Cannabinoid, CB2
/ agonists
Spinal Cord
/ diagnostic imaging
TRPV Cation Channels
/ genetics
DRG
Mouse
Pain
Paraffin immunohistochemistry
Spectral analysis
Journal
Brain research
ISSN: 1872-6240
Titre abrégé: Brain Res
Pays: Netherlands
ID NLM: 0045503
Informations de publication
Date de publication:
01 01 2022
01 01 2022
Historique:
received:
08
08
2021
revised:
02
11
2021
accepted:
05
11
2021
pubmed:
15
11
2021
medline:
29
3
2022
entrez:
14
11
2021
Statut:
ppublish
Résumé
The transient receptor potential (TRP) superfamily of cation channels, of which the TRP vanilloid type 1 (TRPV1) receptor plays a critical role in inflammatory and neuropathic pain, is expressed on nociceptors and spinal cord dorsal horn neurons. TRPV1 is also expressed on spinal astrocytes and dorsal root ganglia (DRG) satellite cells. Agonists of the cannabinoid type 2 receptor (CB
Identifiants
pubmed: 34774500
pii: S0006-8993(21)00578-3
doi: 10.1016/j.brainres.2021.147721
pii:
doi:
Substances chimiques
3-(1,1-dimethyl-heptyl)-1-hydroxy-9-methoxy-benzo(c)chromen-6-one
0
Cannabinoid Receptor Agonists
0
Chemokine CCL2
0
Chromones
0
Glial Fibrillary Acidic Protein
0
Receptor, Cannabinoid, CB2
0
TRPV Cation Channels
0
TRPV1 protein, mouse
0
glial fibrillary astrocytic protein, mouse
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
147721Subventions
Organisme : NIAAA NIH HHS
ID : R01 AA025967
Pays : United States
Organisme : NIAAA NIH HHS
ID : R21 AA023051
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA018156
Pays : United States
Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.