A multi-omics study to boost continuous bolaform sophorolipid production.

Bioreactors Glycolipids Guanosine / analogs & derivatives Industrial Microbiology Metabolomics Oleic Acids / biosynthesis Oxidative Stress Phosphates Surface-Active Agents
8-hydroxyguanosine Biosurfactants Integrated separation Multi-omics Sophorolipids Starmerella bombicola

Journal

New biotechnology
ISSN: 1876-4347
Titre abrégé: N Biotechnol
Pays: Netherlands
ID NLM: 101465345

Informations de publication

Date de publication:
25 Jan 2022
Historique:
received: 24 08 2021
revised: 24 10 2021
accepted: 08 11 2021
pubmed: 15 11 2021
medline: 24 12 2021
entrez: 14 11 2021
Statut: ppublish

Résumé

Biodegradable and biobased surface active agents are renewable and environmentally friendly alternatives to petroleum derived or oleochemical surfactants. However, they are accompanied by relatively high production costs. In this study, the aim was to reduce the production costs for an innovative type of microbial biosurfactant: bolaform sophorolipids, produced by the yeast Starmerella bombicola ΔsbleΔat. A novel continuous retentostat set-up was performed whereby continuous broth microfiltration retained the biomass in the bioreactor while performing an in situ product separation of bolaform sophorolipids. Although a mean volumetric productivity of 0.56 g L

Identifiants

DOI: 10.1016/j.nbt.2021.11.002 PMID: 34774786
pubmed: 34774786
pii: S1871-6784(21)00096-0
doi: 10.1016/j.nbt.2021.11.002
pii:
doi:

Substances chimiques

Glycolipids 0
Oleic Acids 0
Phosphates 0
Surface-Active Agents 0
sophorolipid 0
Guanosine 12133JR80S
8-hydroxyguanosine 3868-31-3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

107-115

Informations de copyright

Copyright © 2021. Published by Elsevier B.V.

Auteurs

Sven Dierickx (S)

Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Ghent University, Ghent, Belgium; Lab of Chemical Analysis (LCA), Ghent University, Merelbeke, Belgium. Electronic address: sven.dierickx@ugent.be.

Karolien Maes (K)

Bio Base Europe Pilot Plant (BBEPP), Ghent, Belgium. Electronic address: karolien.maes@bbeu.org.

Sophie L K W Roelants (SLKW)

Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Ghent University, Ghent, Belgium; Bio Base Europe Pilot Plant (BBEPP), Ghent, Belgium. Electronic address: sophie.roelants@ugent.be.

Beata Pomian (B)

Lab of Chemical Analysis (LCA), Ghent University, Merelbeke, Belgium. Electronic address: beata.pomian@ugent.be.

Lieven Van Meulebroek (L)

Lab of Chemical Analysis (LCA), Ghent University, Merelbeke, Belgium. Electronic address: lieven.vanmeulenbroek@ugent.be.

Sofie L De Maeseneire (SL)

Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Ghent University, Ghent, Belgium. Electronic address: sofie.demaeseneire@ugent.be.

Lynn Vanhaecke (L)

Lab of Chemical Analysis (LCA), Ghent University, Merelbeke, Belgium. Electronic address: lynn.vanhaecke@ugent.beand.

Wim K Soetaert (WK)

Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Ghent University, Ghent, Belgium; Bio Base Europe Pilot Plant (BBEPP), Ghent, Belgium. Electronic address: wim.soetaert@ugent.be.

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Biotechnologie › Bioréacteurs › A multi-omics study to boost continuous...
questionsmedicales.fr › Lipides › Glycolipides › A multi-omics study to boost continuous...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléosides › Ribonucléosides › Guanosine › A multi-omics study to boost continuous...
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Biotechnologie › Microbiologie industrielle › A multi-omics study to boost continuous...
questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Biochimie › Métabolomique › A multi-omics study to boost continuous...
questionsmedicales.fr › Lipides › Acides gras › Acides gras insaturés › Acides gras monoinsaturés › Acides oléiques › A multi-omics study to boost continuous...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › A multi-omics study to boost continuous...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du phosphore › Acides du phosphore › Acides phosphoriques › Phosphates › A multi-omics study to boost continuous...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Tensioactifs › A multi-omics study to boost continuous...