Surveillance of omadacycline activity tested against clinical isolates from the USA: report from the SENTRY Antimicrobial Surveillance Program, 2019.

Anti-Bacterial Agents / pharmacology Methicillin-Resistant Staphylococcus aureus Microbial Sensitivity Tests Tetracyclines
ABSSSI CABP MRSA Omadacycline Surveillance

Journal

Journal of global antimicrobial resistance
ISSN: 2213-7173
Titre abrégé: J Glob Antimicrob Resist
Pays: Netherlands
ID NLM: 101622459

Informations de publication

Date de publication:
12 2021
Historique:
received: 02 02 2021
revised: 13 09 2021
accepted: 15 09 2021
pubmed: 15 11 2021
medline: 31 12 2021
entrez: 14 11 2021
Statut: ppublish

Résumé

Omadacycline was tested against 7000 bacterial isolates collected prospectively from medical centres in the USA during 2019. Antimicrobial susceptibility testing was performed according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Omadacycline was active against: Staphylococcus aureus (MIC The 2019 in vitro activity of omadacycline against key Gram-positive and Gram-negative pathogens has not changed compared with the prior 3 years of surveillance in the SENTRY Antimicrobial Surveillance Program. Omadacycline merits further study in serious infections where resistant pathogens may be encountered.

Identifiants

DOI: 10.1016/j.jgar.2021.09.011 PMID: 34775129
pubmed: 34775129
pii: S2213-7165(21)00235-6
doi: 10.1016/j.jgar.2021.09.011
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Tetracyclines 0
omadacycline 090IP5RV8F

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

337-351

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Michael A Pfaller (MA)

JMI Laboratories, North Liberty, Iowa, USA; University of Iowa, Iowa, City, Iowa, USA.

Michael D Huband (MD)

JMI Laboratories, North Liberty, Iowa, USA. Electronic address: michael-huband@jmilabs.com.

Dee Shortridge (D)

JMI Laboratories, North Liberty, Iowa, USA.

Robert K Flamm (RK)

JMI Laboratories, North Liberty, Iowa, USA.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Surveillance of omadacycline activity tested...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › Surveillance of omadacycline activity tested...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Surveillance of omadacycline activity tested...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Naphtacènes › Tétracyclines › Surveillance of omadacycline activity tested...