Free flap for lower limb salvage in infectious purpura fulminans.


Journal

Annales de chirurgie plastique et esthetique
ISSN: 1768-319X
Titre abrégé: Ann Chir Plast Esthet
Pays: France
ID NLM: 8305839

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 14 09 2021
revised: 10 10 2021
accepted: 18 10 2021
pubmed: 17 11 2021
medline: 15 12 2021
entrez: 16 11 2021
Statut: ppublish

Résumé

Infectious purpura fulminans is a disabling disease often leading to amputations. Free flaps preserve limb length, covering exposed areas. We examined the efficacy of free flaps for lower limb salvage in infectious purpura fulminans survivors by evaluating surgical management, walking ability and quality of life. This single-center, observational, descriptive, retrospective study was conducted in from 2016 to 2019. Adult purpura fulminans survivors who received a free flap for lower limb salvage were included. Patient characteristics and data on surgical management and rehabilitation were collected. Quality of life (SF-36 questionnaire), limb function and walking ability were later evaluated post-surgically. The 6 patients included, mean age 38 years, had all required amputations. Nine free flaps were performed to cover important structures in 7 cases and for stump resurfacing in 2. All flaps were successful. Patients resumed walking at a mean of 204±108 days after the onset of purpura fulminans. Post-surgical evaluation was performed at a mean of 30±9.3 months. Five patients required secondary revision. All were independent for the activities of daily living. Mean physical component score was 37.6±9.4 and mental component score was 44.6±13.2 (minimum 0, maximum 100). Use of the free flap in patients with infectious purpura fulminans, after multidisciplinary reflection, is an appropriate procedure that preserves limb length. In spite of secondary complications, preservation of limb length enables patients to resume walking, with relatively good independence and quality of life.

Sections du résumé

BACKGROUND BACKGROUND
Infectious purpura fulminans is a disabling disease often leading to amputations. Free flaps preserve limb length, covering exposed areas. We examined the efficacy of free flaps for lower limb salvage in infectious purpura fulminans survivors by evaluating surgical management, walking ability and quality of life.
METHODS METHODS
This single-center, observational, descriptive, retrospective study was conducted in from 2016 to 2019. Adult purpura fulminans survivors who received a free flap for lower limb salvage were included. Patient characteristics and data on surgical management and rehabilitation were collected. Quality of life (SF-36 questionnaire), limb function and walking ability were later evaluated post-surgically.
RESULTS RESULTS
The 6 patients included, mean age 38 years, had all required amputations. Nine free flaps were performed to cover important structures in 7 cases and for stump resurfacing in 2. All flaps were successful. Patients resumed walking at a mean of 204±108 days after the onset of purpura fulminans. Post-surgical evaluation was performed at a mean of 30±9.3 months. Five patients required secondary revision. All were independent for the activities of daily living. Mean physical component score was 37.6±9.4 and mental component score was 44.6±13.2 (minimum 0, maximum 100).
CONCLUSIONS CONCLUSIONS
Use of the free flap in patients with infectious purpura fulminans, after multidisciplinary reflection, is an appropriate procedure that preserves limb length. In spite of secondary complications, preservation of limb length enables patients to resume walking, with relatively good independence and quality of life.

Identifiants

pubmed: 34782172
pii: S0294-1260(21)00095-9
doi: 10.1016/j.anplas.2021.10.001
pii:
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

420-428

Informations de copyright

Copyright © 2021 Elsevier Masson SAS. All rights reserved.

Auteurs

J Boucher (J)

Department of Plastic and Reconstructive Surgery and Burn Care Unit, Lille University Hospital, CHU de Lille, 59000 Lille, France. Electronic address: boucher.justine@live.fr.

E Guerre (E)

Department of Orthopaedic Surgery No. 1, Lille University Hospital, Lille, France.

V Duquennoy-Martinot (V)

Department of Plastic and Reconstructive Surgery and Burn Care Unit, Lille University Hospital, CHU de Lille, 59000 Lille, France.

P Guerreschi (P)

Department of Plastic and Reconstructive Surgery and Burn Care Unit, Lille University Hospital, CHU de Lille, 59000 Lille, France.

L Pasquesoone (L)

Department of Plastic and Reconstructive Surgery and Burn Care Unit, Lille University Hospital, CHU de Lille, 59000 Lille, France.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH