Noninvasive detection of spatiotemporal activation-repolarization interactions that prime idiopathic ventricular fibrillation.

Animals Electrocardiography / methods Heart Arrest Heart Ventricles Humans Swine Ventricular Fibrillation / diagnosis

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
17 11 2021
Historique:
entrez: 17 11 2021
pubmed: 18 11 2021
medline: 31 3 2022
Statut: ppublish

Résumé

A comprehensive understanding of the interaction between triggers and electrical substrates leading to ventricular fibrillation (VF) and sudden cardiac arrest is lacking, and electrical substrates are difficult to detect and localize with current clinical tools. Here, we created repolarization time (RT) dispersion by regional drug infusion in perfused explanted human (

Identifiants

DOI: 10.1126/scitranslmed.abi9317 PMID: 34788076
pubmed: 34788076
doi: 10.1126/scitranslmed.abi9317
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabi9317

Auteurs

Matthijs J M Cluitmans (MJM)

Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, Netherlands.
Philips Research, 5656 AE Eindhoven, Netherlands.
ORCID: 0000-0002-3456-7668

Laura R Bear (LR)

IHU LIRYC, 33600 Pessac, France.

Uyên C Nguyên (UC)

Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, Netherlands.
ORCID: 0000-0002-4836-2946

Bianca van Rees (B)

Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, Netherlands.
ORCID: 0000-0002-1388-3039

Job Stoks (J)

Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, Netherlands.
ORCID: 0000-0001-8881-5498

Rachel M A Ter Bekke (RMA)

Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, Netherlands.
ORCID: 0000-0003-4278-0132

Casper Mihl (C)

Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, Netherlands.
Department of Radiology, Maastricht University Medical Centre, 6200 MD Maastricht, Netherlands.

Jordi Heijman (J)

Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, Netherlands.
ORCID: 0000-0002-1418-108X

Kevin D Lau (KD)

Philips Research, 5656 AE Eindhoven, Netherlands.

Edward Vigmond (E)

IHU LIRYC, 33600 Pessac, France.
ORCID: 0000-0003-1388-3589

Jason Bayer (J)

IHU LIRYC, 33600 Pessac, France.
ORCID: 0000-0003-0269-3499

Charly N W Belterman (CNW)

Department of Experimental Cardiology, Amsterdam University Medical Centre, 1105 AZ Amsterdam, Netherlands.
ORCID: 0000-0002-6213-1693

Emma Abell (E)

IHU LIRYC, 33600 Pessac, France.
ORCID: 0000-0002-8180-1787

Louis Labrousse (L)

IHU LIRYC, 33600 Pessac, France.
University of Bordeaux, 33000 Bordeaux, France.
Hôpital Haut Lévêque, University Hospital of Bordeaux, 33604 Bordeaux, France.
ORCID: 0000-0001-8542-9049

Julien Rogier (J)

IHU LIRYC, 33600 Pessac, France.
University of Bordeaux, 33000 Bordeaux, France.
Hôpital Haut Lévêque, University Hospital of Bordeaux, 33604 Bordeaux, France.
ORCID: 0000-0002-5067-4439

Olivier Bernus (O)

IHU LIRYC, 33600 Pessac, France.
University of Bordeaux, 33000 Bordeaux, France.

Michel Haïssaguerre (M)

IHU LIRYC, 33600 Pessac, France.
University of Bordeaux, 33000 Bordeaux, France.
Hôpital Haut Lévêque, University Hospital of Bordeaux, 33604 Bordeaux, France.
ORCID: 0000-0001-7644-6146

Rutger J Hassink (RJ)

Department of Cardiology, University Medical Centre Utrecht, 3584 CX Utrecht, Netherlands.

Rémi Dubois (R)

IHU LIRYC, 33600 Pessac, France.
ORCID: 0000-0002-3320-6086

Ruben Coronel (R)

IHU LIRYC, 33600 Pessac, France.
Department of Experimental Cardiology, Amsterdam University Medical Centre, 1105 AZ Amsterdam, Netherlands.
ORCID: 0000-0001-9433-6119

Paul G A Volders (PGA)

Cardiovascular Research Institute Maastricht, Maastricht University, 6200 MD Maastricht, Netherlands.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Noninvasive detection of spatiotemporal...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Électrodiagnostic › Électrocardiographie › Noninvasive detection of spatiotemporal...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Arrêt cardiaque › Noninvasive detection of spatiotemporal...
questionsmedicales.fr › Système cardiovasculaire › Coeur › Ventricules cardiaques › Noninvasive detection of spatiotemporal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Noninvasive detection of spatiotemporal...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Noninvasive detection of spatiotemporal...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles du rythme cardiaque › Fibrillation ventriculaire › Noninvasive detection of spatiotemporal...