Role of magnetic resonance spectroscopy in differential diagnosis of solitary pulmonary lesions.


Journal

Diagnostic and interventional radiology (Ankara, Turkey)
ISSN: 1305-3612
Titre abrégé: Diagn Interv Radiol
Pays: Turkey
ID NLM: 101241152

Informations de publication

Date de publication:
Nov 2021
Historique:
entrez: 18 11 2021
pubmed: 19 11 2021
medline: 20 11 2021
Statut: ppublish

Résumé

The aim of our study was to evaluate the availability of magnetic resonance spectroscopy (MRS) for the differentiation of benign or malignant pulmonary nodules and masses. A total of 59 patients (45 male, 14 female) with pulmonary nodules and masses were included in this prospective study. MRS was applied to the pulmonary lesions of the patients and choline levels were determined. Afterwards CT-guided percutaneous needle biopsy was performed. According to the biopsy results, pulmonary lesions were benign in 25 patients and malignant in 34 patients. Choline levels were significantly higher in malignant lesions compared with benign lesions (p < 0.001). When the other conditions were kept constant, the probability of malignancy significantly increased by 17.38-fold (95% CI, 3.78-79.93) in those with choline levels >1.65 µmol/g compared to those with choline levels ≤1.65 µmol/g (p < 0.001). MRS is a noninvasive method that can be used in the differential diagnosis of pulmonary nodules and masses.

Identifiants

pubmed: 34792024
doi: 10.5152/dir.2021.20419
pmc: PMC8621646
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

710-715

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Auteurs

Azad Hekimoglu (A)

Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Onur Ergun (O)

Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Aynur Turan (A)

Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Tugba Taskin Turkmenoglu (T)

Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

Baki Hekimoglu (B)

Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

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