Glycine Transporters and Receptors as Targets for Analgesics.

Analgesics / pharmacology Glycine Glycine Plasma Membrane Transport Proteins / genetics Receptors, Glycine / genetics Synaptic Transmission

Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
11 11 2021
Historique:
received: 27 10 2021
revised: 30 11 2021
accepted: 04 11 2021
entrez: 27 11 2021
pubmed: 28 11 2021
medline: 15 12 2021
Statut: epublish

Résumé

The suitability of modulating glycinergic neurotransmission for the treatment of inflammatory and chronic pain has gained widespread recognition, with glycine receptors (GlyRs) and glycine transporters (GlyT1 and GlyT2) now considered key therapeutic targets [...].

Identifiants

DOI: 10.3390/biom11111676 PMID: 34827674 PMC: PMC8615606
pubmed: 34827674
pii: biom11111676
doi: 10.3390/biom11111676
pmc: PMC8615606
pii:
doi:

Substances chimiques

Analgesics 0
Glycine Plasma Membrane Transport Proteins 0
Receptors, Glycine 0
Glycine TE7660XO1C

Types de publication

Editorial Comment

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentOn

Références

Biomolecules. 2021 Jun 10;11(6):
pubmed: 34200954
Brain. 2018 Jan 1;141(1):63-71
pubmed: 29149236
Nat Rev Drug Discov. 2013 Nov;12(11):866-85
pubmed: 24172334
Biomolecules. 2020 Nov 30;10(12):
pubmed: 33266066
Science. 2004 May 7;304(5672):884-7
pubmed: 15131310
Cell Mol Life Sci. 2018 Feb;75(3):447-465
pubmed: 28791431
Biomolecules. 2021 Jun 06;11(6):
pubmed: 34204137
Biomolecules. 2021 Mar 25;11(4):
pubmed: 33805979
Biomolecules. 2021 Jun 24;11(7):
pubmed: 34202809

Auteurs

Robert J Harvey (RJ)

School of Health and Behavioural Sciences, University of the Sunshine Coast, Maroochydore, QLD 4556, Australia.
Sunshine Coast Health Institute, Birtinya, QLD 4558, Australia.
ORCID: 0000-0001-5956-6664

Robert J Vandenberg (RJ)

School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Analgésiques › Glycine Transporters and Receptors as Targets...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Glycine › Glycine Transporters and Receptors as Targets...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Transporteurs de neurotransmetteurs › Transporteurs plasmiques de neurotransmetteurs › Transporteurs de la glycine › Glycine Transporters and Receptors as Targets...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteur de la glycine › Glycine Transporters and Receptors as Targets...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Transmission synaptique › Glycine Transporters and Receptors as Targets...