Analgesic regimens administered to older adults receiving skilled nursing facility care following hip fracture: a proof-of-concept federated analysis.


Journal

BMC geriatrics
ISSN: 1471-2318
Titre abrégé: BMC Geriatr
Pays: England
ID NLM: 100968548

Informations de publication

Date de publication:
30 Oct 2024
Historique:
received: 03 07 2024
accepted: 16 10 2024
medline: 31 10 2024
pubmed: 31 10 2024
entrez: 31 10 2024
Statut: epublish

Résumé

Although a majority of patients in the U.S. receive post-acute care in skilled nursing facilities (SNFs) following hip fracture, large-sample observational studies of analgesic prescribing and use in SNFs have not been possible due to limitations in available data sources. We conducted a proof-of-concept federated analysis of electronic health records (EHRs) from 11 SNF chains to describe analgesic use during hip fracture post-acute care. We included residents with a diagnosis of hip fracture between January 1, 2018 and June 30, 2021 who had at least one administration of an analgesic. Use of analgesics was ascertained from EHR medication orders and medication administration records. We quantified the proportion of residents receiving analgesic regimens based on the medications that were administered up to 100 days after hip fracture diagnosis. Plots visualizing trends in analgesic use were stratified by multiple resident characteristics including age and Alzheimer's Disease and Related Dementias (ADRD) diagnosis. The study included 23,706 residents (mean age 80.5 years, 68.6% female, 87.7% White). Most (~ 60%) residents received opioids + APAP. Monotherapy with APAP or opioids was also common. The most prevalent regimens were oxycodone + APAP (20.1%), hydrocodone + APAP (15.8%), APAP only (15.1%), tramadol + APAP (10.4%), and oxycodone only (4.3%). During the study period, use of APAP-only increased, opioids-only decreased, and opioids + APAP remained stable. Use of APAP-only appeared to be more prevalent among individuals aged > 75 years (versus ≤ 75 years) and those with ADRD (versus without). We successfully leveraged federated SNF EHR data to describe analgesic use among residents receiving hip fracture post-acute care.

Sections du résumé

BACKGROUND BACKGROUND
Although a majority of patients in the U.S. receive post-acute care in skilled nursing facilities (SNFs) following hip fracture, large-sample observational studies of analgesic prescribing and use in SNFs have not been possible due to limitations in available data sources. We conducted a proof-of-concept federated analysis of electronic health records (EHRs) from 11 SNF chains to describe analgesic use during hip fracture post-acute care.
METHODS METHODS
We included residents with a diagnosis of hip fracture between January 1, 2018 and June 30, 2021 who had at least one administration of an analgesic. Use of analgesics was ascertained from EHR medication orders and medication administration records. We quantified the proportion of residents receiving analgesic regimens based on the medications that were administered up to 100 days after hip fracture diagnosis. Plots visualizing trends in analgesic use were stratified by multiple resident characteristics including age and Alzheimer's Disease and Related Dementias (ADRD) diagnosis.
RESULTS RESULTS
The study included 23,706 residents (mean age 80.5 years, 68.6% female, 87.7% White). Most (~ 60%) residents received opioids + APAP. Monotherapy with APAP or opioids was also common. The most prevalent regimens were oxycodone + APAP (20.1%), hydrocodone + APAP (15.8%), APAP only (15.1%), tramadol + APAP (10.4%), and oxycodone only (4.3%). During the study period, use of APAP-only increased, opioids-only decreased, and opioids + APAP remained stable. Use of APAP-only appeared to be more prevalent among individuals aged > 75 years (versus ≤ 75 years) and those with ADRD (versus without).
CONCLUSIONS CONCLUSIONS
We successfully leveraged federated SNF EHR data to describe analgesic use among residents receiving hip fracture post-acute care.

Identifiants

pubmed: 39478461
doi: 10.1186/s12877-024-05486-0
pii: 10.1186/s12877-024-05486-0
doi:

Substances chimiques

Analgesics 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

897

Informations de copyright

© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.

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Auteurs

Andrew R Zullo (AR)

Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S121-2, Providence, RI, 02912, USA. Andrew_Zullo@brown.edu.
Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA. Andrew_Zullo@brown.edu.
Center for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, RI, USA. Andrew_Zullo@brown.edu.
Center of Innovation in Long-Term Services and Supports, Providence Veterans Affairs Medical Center, Providence, RI, USA. Andrew_Zullo@brown.edu.

Melissa R Riester (MR)

Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S121-2, Providence, RI, 02912, USA.
Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Center for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, RI, USA.

Kaleen N Hayes (KN)

Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Center for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, RI, USA.
Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Toronto Leslie Dan, Toronto, ON, Canada.

Yuan Zhang (Y)

Center for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, RI, USA.

Sarah D Berry (SD)

Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA, USA.
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.

Emmanuelle Belanger (E)

Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Center for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, RI, USA.

Meghan A Cupp (MA)

Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S121-2, Providence, RI, 02912, USA.

Francesca L Beaudoin (FL)

Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Box G-S121-2, Providence, RI, 02912, USA.

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