Risk of Developing Metabolic Syndrome Is Affected by Length of Daily Siesta: Results from a Prospective Cohort Study.
dyslipidaemia
hypertension
metabolic syndrome
nap
obesity
siesta
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
22 Nov 2021
22 Nov 2021
Historique:
received:
28
10
2021
revised:
17
11
2021
accepted:
19
11
2021
entrez:
27
11
2021
pubmed:
28
11
2021
medline:
15
12
2021
Statut:
epublish
Résumé
Siesta has been associated with increased incidence of cardiovascular disease but the mechanism remains unclear. New studies into the relationship between siesta and metabolic syndrome have identified siesta length as a crucial differential, suggesting that siesta less than 40 min is associated with decreased risk of metabolic syndrome, while longer siesta is associated with increased risk. We aimed to investigate the effect of siesta duration on development of metabolic syndrome in a Mediterranean population using a prospective cohort study design. Our sample consisted of 9161 participants of the SUN cohort without components of metabolic syndrome at baseline. Siesta exposure was assessed at baseline and the development of metabolic syndrome components was assessed after an average 6.8 years of follow-up. We estimated odds ratios and fitted logistic regression models to adjust for potential cofounders including night-time sleep duration and quality, as well as other diet, health, and lifestyle factors. We observed a positive association between average daily siesta >30 min and development of metabolic syndrome (aOR = 1.39 CI: 1.03-1.88). We found no significant difference in risk of developing metabolic syndrome between the group averaging ≤30 min of daily siesta and the group not taking siesta (aOR = 1.07 CI: 0.83-1.37). Further analysis suggested that average daily siesta <15 min may reduce risk of metabolic syndrome. Our study supports the J-curve model of the association between siesta and risk of metabolic syndrome, but suggests the protective effect is limited to a shorter range of siesta length than previously proposed.
Sections du résumé
BACKGROUND
BACKGROUND
Siesta has been associated with increased incidence of cardiovascular disease but the mechanism remains unclear. New studies into the relationship between siesta and metabolic syndrome have identified siesta length as a crucial differential, suggesting that siesta less than 40 min is associated with decreased risk of metabolic syndrome, while longer siesta is associated with increased risk. We aimed to investigate the effect of siesta duration on development of metabolic syndrome in a Mediterranean population using a prospective cohort study design.
METHODS
METHODS
Our sample consisted of 9161 participants of the SUN cohort without components of metabolic syndrome at baseline. Siesta exposure was assessed at baseline and the development of metabolic syndrome components was assessed after an average 6.8 years of follow-up. We estimated odds ratios and fitted logistic regression models to adjust for potential cofounders including night-time sleep duration and quality, as well as other diet, health, and lifestyle factors.
RESULTS
RESULTS
We observed a positive association between average daily siesta >30 min and development of metabolic syndrome (aOR = 1.39 CI: 1.03-1.88). We found no significant difference in risk of developing metabolic syndrome between the group averaging ≤30 min of daily siesta and the group not taking siesta (aOR = 1.07 CI: 0.83-1.37). Further analysis suggested that average daily siesta <15 min may reduce risk of metabolic syndrome.
CONCLUSIONS
CONCLUSIONS
Our study supports the J-curve model of the association between siesta and risk of metabolic syndrome, but suggests the protective effect is limited to a shorter range of siesta length than previously proposed.
Identifiants
pubmed: 34836438
pii: nu13114182
doi: 10.3390/nu13114182
pmc: PMC8619148
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : European Research Council
ID : Agreement 340918
Pays : International
Organisme : Instituto de Salud Carlos III
ID : RD 06/0045, CIBER-OBN, Grants PI13/00615, PI10/02658, PI10/02293, PI13/00615, PI14/01668, PI14/01798, PI14/01764, PI17/01795 and G03/140
Organisme : Comunidad Foral de Navarra
ID : 27/2011, 45/2011, 122/2014
Organisme : University of Navarra
Références
Endocrine. 2013 Dec;44(3):634-47
pubmed: 23546613
Sleep. 2010 Mar;33(3):402-7
pubmed: 20337199
Heart. 2019 Dec;105(23):1793-1798
pubmed: 31501230
Sleep Med Rev. 2010 Aug;14(4):249-58
pubmed: 19962331
Sleep Breath. 2018 Sep;22(3):815-824
pubmed: 28612266
Soc Psychiatry Psychiatr Epidemiol. 2018 Nov;53(11):1149-1160
pubmed: 30182156
Diabetes Metab. 2014 Nov;40(5):338-46
pubmed: 24433933
Sleep. 2016 Nov 01;39(11):1911-1918
pubmed: 27450688
BMC Public Health. 2011 Nov 15;11:867
pubmed: 22085407
J Clin Sleep Med. 2015 Jun 15;11(6):591-2
pubmed: 25979105
Sci Rep. 2016 Dec 02;6:38075
pubmed: 27909305
Int J Epidemiol. 2010 Feb;39(1):233-43
pubmed: 19900974
J Hypertens. 2014 Oct;32(10):1993-8; discussion 1998
pubmed: 25023156
PLoS One. 2019 Oct 16;14(10):e0223665
pubmed: 31618237
Sleep. 2005 Mar;28(3):345-7
pubmed: 16173656
Lancet. 2008 Jun 7;371(9628):1927-35
pubmed: 18501419
N Engl J Med. 2003 Jun 26;348(26):2599-608
pubmed: 12826634
Atherosclerosis. 2010 May;210(1):237-42
pubmed: 19945701
Sleep Health. 2020 Oct;6(5):684-689
pubmed: 32482574
Sleep Med. 2015 Jul;16(7):811-9
pubmed: 26051864
Am J Surg. 2020 Aug;220(2):448-453
pubmed: 31879020
Nat Commun. 2017 Sep 12;8(1):417
pubmed: 28900189
J Am Geriatr Soc. 2009 Apr;57(4):604-11
pubmed: 19220560
J Am Coll Cardiol. 2010 Sep 28;56(14):1113-32
pubmed: 20863953
Chest. 2018 Jan;153(1):87-93
pubmed: 28970105
Diabetes Care. 2005 Jul;28(7):1769-78
pubmed: 15983333
Sleep. 2012 Dec 01;35(12):1705-12
pubmed: 23204613
Annu Rev Physiol. 2016;78:109-31
pubmed: 26208951
Gac Sanit. 2011 Jul-Aug;25(4):303-7
pubmed: 21543137
Diabetes Care. 2012 Nov;35(11):2402-11
pubmed: 23093685
JAMA. 2004 Nov 10;292(18):2237-42
pubmed: 15536110
Sleep. 2003 Aug 1;26(5):578-84
pubmed: 12938811
Circulation. 2009 Oct 20;120(16):1640-5
pubmed: 19805654
Ann Intern Med. 2006 Jun 6;144(11):785-91
pubmed: 16754920
Sleep Med. 2019 May;57:128-134
pubmed: 30981956
Sleep. 2002 Mar 15;25(2):187-91
pubmed: 11902427
Sleep Med. 2018 Dec;52:51-57
pubmed: 30278295
Psychophysiology. 2014 Nov;51(11):1131-8
pubmed: 24961384
Med Sci Monit. 2015 May 04;21:1269-75
pubmed: 25937468
Metabolism. 2014 Dec;63(12):1520-7
pubmed: 25249445
Nutrients. 2018 Mar 31;10(4):
pubmed: 29614726
Metabolism. 2018 Jul;84:56-66
pubmed: 29510179
J Gastrointest Surg. 2019 Apr;23(4):739-744
pubmed: 30430431
Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4453-8
pubmed: 19255424
Nat Rev Cardiol. 2019 Jul;16(7):437-447
pubmed: 30796369
Int J Environ Res Public Health. 2020 Jun 15;17(12):
pubmed: 32549270
Sleep Med. 2016 Jan;17:144-8
pubmed: 26847990
Sleep. 2005 Jul;28(7):829-36
pubmed: 16124661
Sleep Med. 2017 Sep;37:105-112
pubmed: 28899519
Obes Facts. 2013;6(4):337-47
pubmed: 23970143
J Sleep Res. 2016 Apr;25(2):225-33
pubmed: 26718988
Chest. 2019 Aug;156(2):348-356
pubmed: 30853108
Am J Epidemiol. 2014 May 1;179(9):1115-24
pubmed: 24685532
Lancet. 1987 Aug 1;2(8553):269-70
pubmed: 2886731
Arch Intern Med. 1999 Jul 26;159(14):1582-6
pubmed: 10421281
Int J Epidemiol. 2000 Jun;29(3):429-37
pubmed: 10869314