Whole Blood Versus Conventional Blood Component Massive Transfusion Protocol Therapy in Civilian Trauma Patients.
blood component therapy
hemorrhage
resuscitation
trauma
whole blood
Journal
The American surgeon
ISSN: 1555-9823
Titre abrégé: Am Surg
Pays: United States
ID NLM: 0370522
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
pubmed:
30
11
2021
medline:
15
4
2022
entrez:
29
11
2021
Statut:
ppublish
Résumé
Military data demonstrating an improved survival rate with whole blood (WB) have led to a shift toward the use of WB in civilian trauma. The purpose of this study is to compare a low-titer group O WB (LTOWB) massive transfusion protocol (MTP) to conventional blood component therapy (BCT) MTP in civilian trauma patients. Trauma patients 15 years or older who had MTP activations from February 2019 to December 2020 were included. Patients with a LTOWB MTP activation were compared to BCT MTP patients from a historic cohort. 299 patients were identified, 169 received LTOWB and 130 received BCT. There were no differences in age, gender, or injury type. The Injury Severity Score was higher in the BCT group (27 vs 25, Resuscitating severely injured trauma patient with LTOWB is safe and may be associated with an improved survival.
Sections du résumé
BACKGROUND
BACKGROUND
Military data demonstrating an improved survival rate with whole blood (WB) have led to a shift toward the use of WB in civilian trauma. The purpose of this study is to compare a low-titer group O WB (LTOWB) massive transfusion protocol (MTP) to conventional blood component therapy (BCT) MTP in civilian trauma patients.
METHODS
METHODS
Trauma patients 15 years or older who had MTP activations from February 2019 to December 2020 were included. Patients with a LTOWB MTP activation were compared to BCT MTP patients from a historic cohort.
RESULTS
RESULTS
299 patients were identified, 169 received LTOWB and 130 received BCT. There were no differences in age, gender, or injury type. The Injury Severity Score was higher in the BCT group (27 vs 25,
DISCUSSION
CONCLUSIONS
Resuscitating severely injured trauma patient with LTOWB is safe and may be associated with an improved survival.
Identifiants
pubmed: 34839732
doi: 10.1177/00031348211049752
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM