Oxytocin variation and brain region-specific gene expression in a domesticated avian species.
domestication
gene expression
inter-strain difference
intra-strain variability
mesotocin
oxytocin
songbird
Journal
Genes, brain, and behavior
ISSN: 1601-183X
Titre abrégé: Genes Brain Behav
Pays: England
ID NLM: 101129617
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
revised:
07
11
2021
received:
18
03
2021
accepted:
09
11
2021
pubmed:
3
12
2021
medline:
19
4
2022
entrez:
2
12
2021
Statut:
ppublish
Résumé
The Bengalese finch was domesticated more than 250 years ago from the wild white-rumped munia (WRM). Similar to other domesticated species, Bengalese finches show a reduced fear response and have lower corticosterone levels, compared to WRMs. Bengalese finches and munias also have different song types. Since oxytocin (OT) has been found to be involved in stress coping and auditory processing, we tested whether the OT sequence and brain expression pattern and content differ in wild munias and domesticated Bengalese finches. We sequenced the OT from 10 wild munias and 11 Bengalese finches and identified intra-strain variability in both the untranslated and protein-coding regions of the sequence, with all the latter giving rise to synonymous mutations. Several of these changes fall in specific transcription factor-binding sites, and show either a conserved or a relaxed evolutionary trend in the avian lineage, and in vertebrates in general. Although in situ hybridization in several hypothalamic nuclei did not reveal significant differences in the number of cells expressing OT between the two strains, real-time quantitative PCR showed a significantly higher OT mRNA expression in the cerebrum of the Bengalese finches relative to munias, but a significantly lower expression in their diencephalon. Our study thus points to a brain region-specific pattern of neurochemical expression in domesticated and wild avian strains, which could be linked to domestication and the behavioral changes associated with it.
Identifiants
pubmed: 34854547
doi: 10.1111/gbb.12780
pmc: PMC9744569
doi:
Substances chimiques
Oxytocin
50-56-6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12780Subventions
Organisme : Ministry of Education, Culture, Sports, Science and Technology Japan
ID : JP16K18585
Organisme : Ministry of Education, Culture, Sports, Science and Technology Japan
ID : JP19K06751
Organisme : Moritani Scholarship Foundation
Organisme : Rockefeller University
Organisme : Spanish Science Ministry
ID : PID2019-107042GB-I00
Organisme : Howard Hughes Medical Institute
Pays : United States
Informations de copyright
© 2021 The Authors. Genes, Brain and Behavior published by International Behavioural and Neural Genetics Society and John Wiley & Sons Ltd.
Références
Proc Biol Sci. 2013 Jan 7;280(1750):20122396
pubmed: 23173212
Horm Behav. 2012 Jul;62(2):113-9
pubmed: 22633910
Horm Behav. 2013 Jun;64(1):103-12
pubmed: 23722238
J Exp Zool A Ecol Genet Physiol. 2012 Nov;317(9):561-70
pubmed: 22927235
Cell Tissue Res. 1977 Oct 21;184(1):1-13
pubmed: 922855
Science. 2009 Aug 14;325(5942):862-6
pubmed: 19679811
Gen Comp Endocrinol. 2018 Jan 15;256:63-70
pubmed: 28765073
Endocrinology. 2011 Dec;152(12):4865-81
pubmed: 22067316
Neuropsychopharmacology. 2011 Oct;36(11):2159-68
pubmed: 21677650
Science. 2010 May 21;328(5981):1036-40
pubmed: 20378774
Horm Behav. 2020 Sep;125:104820
pubmed: 32710887
Cell Tissue Res. 2019 Jan;375(1):295-307
pubmed: 30357546
Nucleic Acids Res. 2018 Feb 28;46(4):1878-1894
pubmed: 29361190
Physiol Behav. 2015 Mar 15;141:154-63
pubmed: 25598416
Behav Processes. 2013 Nov;100:58-63
pubmed: 23962671
Neuropsychopharmacology. 2014 Dec;39(13):3027-35
pubmed: 24964815
PLoS One. 2018 Apr 2;13(4):e0195407
pubmed: 29608621
Nature. 2010 Apr 1;464(7289):757-62
pubmed: 20360741
Horm Behav. 2017 Jan;87:16-24
pubmed: 27793769
Physiol Behav. 2005 Jun 30;85(3):354-62
pubmed: 15935410
Dev Neurobiol. 2022 Jan;82(1):3-15
pubmed: 34562056
J Neurosci. 1988 Oct;8(10):3785-96
pubmed: 2903913
Gigascience. 2018 Mar 1;7(3):1-6
pubmed: 29618046
Proc Biol Sci. 2017 Jul 26;284(1859):
pubmed: 28724738
Nature. 2021 Apr;592(7856):747-755
pubmed: 33911268
Brain Struct Funct. 2017 Jan;222(1):481-514
pubmed: 27160258
ScientificWorldJournal. 2011 Feb 14;11:429-36
pubmed: 21336458
J Neuroendocrinol. 2000 Mar;12(3):235-43
pubmed: 10718919
PLoS One. 2012;7(8):e43059
pubmed: 22916206
Nature. 2021 Apr;592(7856):737-746
pubmed: 33911273
Neural Plast. 2018 Jul 2;2018:4864107
pubmed: 30057594
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6661-5
pubmed: 293752
Behav Processes. 2021 Dec;193:104503
pubmed: 34537267
Science. 2008 Nov 7;322(5903):900-4
pubmed: 18988842
PLoS One. 2017 Oct 18;12(10):e0185306
pubmed: 29045412
Curr Biol. 2018 Apr 2;28(7):1066-1078.e6
pubmed: 29551417
Genetics. 2014 Jul;197(3):795-808
pubmed: 25024034
Behav Processes. 2021 Dec;193:104502
pubmed: 34530107
Science. 2015 Apr 17;348(6232):333-6
pubmed: 25883356
Psychoneuroendocrinology. 2018 Oct;96:84-92
pubmed: 29909294
Gen Comp Endocrinol. 2004 Dec;139(3):191-7
pubmed: 15560865
Proc Biol Sci. 2017 Aug 30;284(1861):
pubmed: 28835557
Genes Brain Behav. 2017 Apr;16(4):427-438
pubmed: 27860243
J Neuroendocrinol. 1997 Oct;9(10):777-87
pubmed: 9355047
Horm Behav. 2014 Jul;66(2):267-75
pubmed: 24780145
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
Genes Brain Behav. 2022 Feb;21(2):e12780
pubmed: 34854547
Horm Behav. 2021 Feb;128:104901
pubmed: 33245878
Psychon Bull Rev. 2017 Feb;24(1):106-110
pubmed: 28120319
Neurosci Res (N Y). 1971;4:165-212
pubmed: 4948604
J Neuroendocrinol. 2011 Sep;23(9):791-803
pubmed: 21696471
Cell Tissue Res. 1980;213(1):37-51
pubmed: 7459995
Nucleic Acids Res. 2010 Jul;38(Web Server issue):W7-13
pubmed: 20435676
Nat Neurosci. 2020 Sep;23(9):1125-1137
pubmed: 32719563
PLoS Biol. 2003 Nov;1(2):E58
pubmed: 14624258
Horm Behav. 2004 Feb;45(2):136-43
pubmed: 15019801
Prog Brain Res. 2002;139:147-62
pubmed: 12436933
J Neuroendocrinol. 2017 Nov;29(11):
pubmed: 28872712
Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):6069-74
pubmed: 24711411
Anat Sci Int. 2016 Sep;91(4):358-70
pubmed: 26553093