Double anchor lock fixing method to prevent stent displacement in endoscopic ultrasound-guided gastroenterostomy: a porcine study.


Journal

Surgical endoscopy
ISSN: 1432-2218
Titre abrégé: Surg Endosc
Pays: Germany
ID NLM: 8806653

Informations de publication

Date de publication:
07 2022
Historique:
received: 21 09 2020
accepted: 19 10 2021
pubmed: 4 12 2021
medline: 7 6 2022
entrez: 3 12 2021
Statut: ppublish

Résumé

Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is widely used in patients with gastric outlet obstruction (GOO). Recurrence of obstruction symptoms caused by stent migration is the major reason for reintervention in EUS-GE. To solve this problem, we proposed developing a double anchor lock (DAL) fixing stent method for EUS-GE. The safety and efficacy of the DAL fixing stent method were evaluated in this study. Sixteen Bama miniature pigs were randomly divided into an experimental group (n = 8) and a control group (n = 8). A gastric outlet obstruction model was established for all the pigs. The experimental group was treated with the DAL fixing stent method for EUS-GE, while the control group was treated with EUS-GE. Three-month stent migration rate, remission rate of GOO, re-occlusion intervention rate, weight change, and incidence of procedure-related complications of EUS-GE were analyzed and estimated in the two groups. EUS-GE was successfully completed in every subject in both groups. Symptoms of digestive tract obstruction can be relieved in all animals. The stent existence rate in the 3 months was higher in the experimental group than in the control group (87.5% vs. 12.5%, P = 0.012). Except for one animal in the experimental group in which there was pneumoperitoneum due to a stent insertion failure, no animal experienced bleeding or perforation. The DAL fixing stent method, which can effectively prevent stent migration, is safe and simple. EUS-GE can effectively relieve the symptoms of digestive tract obstruction.

Sections du résumé

BACKGROUND
Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is widely used in patients with gastric outlet obstruction (GOO). Recurrence of obstruction symptoms caused by stent migration is the major reason for reintervention in EUS-GE. To solve this problem, we proposed developing a double anchor lock (DAL) fixing stent method for EUS-GE. The safety and efficacy of the DAL fixing stent method were evaluated in this study.
METHODS
Sixteen Bama miniature pigs were randomly divided into an experimental group (n = 8) and a control group (n = 8). A gastric outlet obstruction model was established for all the pigs. The experimental group was treated with the DAL fixing stent method for EUS-GE, while the control group was treated with EUS-GE. Three-month stent migration rate, remission rate of GOO, re-occlusion intervention rate, weight change, and incidence of procedure-related complications of EUS-GE were analyzed and estimated in the two groups.
RESULTS
EUS-GE was successfully completed in every subject in both groups. Symptoms of digestive tract obstruction can be relieved in all animals. The stent existence rate in the 3 months was higher in the experimental group than in the control group (87.5% vs. 12.5%, P = 0.012). Except for one animal in the experimental group in which there was pneumoperitoneum due to a stent insertion failure, no animal experienced bleeding or perforation.
CONCLUSION
The DAL fixing stent method, which can effectively prevent stent migration, is safe and simple. EUS-GE can effectively relieve the symptoms of digestive tract obstruction.

Identifiants

pubmed: 34859303
doi: 10.1007/s00464-021-08834-y
pii: 10.1007/s00464-021-08834-y
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4854-4861

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Haixin Gao (H)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China.

Siyu Sun (S)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China. sun-siyu@163.com.

Guoxin Wang (G)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China.

Jintao Guo (J)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China.

Sheng Wang (S)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China.

Xiang Liu (X)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China.

Nan Ge (N)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China.

Jitong Jiang (J)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China.

Shiyun Sheng (S)

Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China.

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